
Forsker hos Laboratorie for Mikrobiell Genteknologi ledet av Morten Kjos.
Forskning
- LsbB familien med lederløse bakteriociner
- Posisjon-2 proteasen RseP
- Mekanismer for antibiotika-resistens i S. aureus
- Bakterielle stress-respons systemer
- Saposin-lignende bacteriociner
Fagfelt
- Molecular Biology
- Biochemistry
- Bioinformatics
- Molecular Dynamics
- Programming
Publikasjoner
Forskerprofil med publikasjoner i vitenarkivet
Oftedal, T.F., Løvdal, T., Kjos, M. (2025). The phage shock protein response of Listeria monocytogenes influences tolerance to the multipeptide bacteriocin garvicin KS. bioRxiv. [PREPRINT].
Arbulu, S., Oftedal, F. F., Kjos, M. (2025). Transcriptomic response in planktonic and biofilm-associated cells of Streptococcus mutans treated with sublethal concentrations of chlorhexidine. FEMS Microbiology Letters.
Kranjec, C., Oftedal, T. F., Ovchinnikov, K. V., da Silva Duarte, V., Hermansen, S., Kaus-Drobek, M., Sabała, I., Porcellato, D., Carlsen, H., & Kjos, M. (2025). An antibiotic-free antimicrobial combination of bacteriocins and a peptidoglycan hydrolase: in vitro and in vivo assessment of its efficacy. Applied and Environmental Microbiology.
Oftedal, T.F., Diep, D. B., Kjos, M. (2024). Design of Novel Saposin-like Bacteriocins Using a Hybrid Approach. Probiotics and Antimicrobial Proteins.
Wolden R, Ovchinnikov KV, Venter HJ, Oftedal TF, Diep DB, Cavanagh JP. (2023). The novel bacteriocin romsacin from Staphylococcus haemolyticus inhibits Gram-positive WHO priority pathogens. Microbiology Spectrum 11(6): e00869-23.
Oftedal, T.F. (2023) Bacteriocins: from discovery to characterization and applications. Doktoravhandling tilgjengelig: https://hdl.handle.net/11250/3098644
Oftedal, T. F. (2023). Design of Novel Saposin-like Bacteriocins with Antimicrobial Acitivity using a Hybrid Approach. Poster presentasjon: IBA Annual Meeting, Oktober 9-10, Clarion Hotell Bjørvika, Oslo, Norge.
Oftedal, T. F. & Diep, D. B. (2023). Flow cytometric detection of vancomycin-resistant Enterococcus faecium in urine using fluorescently labelled enterocin K1. Sci Rep 13, 10930.
Oftedal, T.F. (2023). Detection of E. faecium using the specific interaction of a bacteriocin EntK1 with its receptor. Muntlig presentasjon: Bacteriocin International Conference 2023, Juni 19-21, Lille, Frankrike.
Oftedal, T. F. (2022). Identification of a Novel Two-Peptide Lantibiotic from Vagococcus fluvialis. Poster presentasjon: 7th International Symposium on Antimicrobial Peptides - AMP2022, November 7-9, Institut Pasteur, Paris, Frankrike.
Kristensen, S. S., Oftedal, T. F., Røhr, Å. K., Eijsink, V. G. H., Mathiesen, G., & Diep, D. B. (2022). The extracellular domain of site-2-metalloprotease RseP is important for sensitivity to bacteriocin EntK1. J. Biol. Chem. In Press. 102593.
Ovchinnikov, K. V., Oftedal, T. F., Reich, S. J., Bar, N. S., Holo, H., Skaugen, M., Riedel, C. U. and Diep, D. B. (2022). Genome-assisted Identification, Purification, and Characterization of Bacteriocins. Bio-protocol 12(14): e4477.
Oftedal, T.F. (2022). Genome-assisted identification, purification and characterization of a novel bacteriocin. Muntlig presentasjon: International Scientific Conference on Probiotics, Prebiotics, Gut Microbiota and Health, June 27-30, Bratislava, Slovakia.
Rosenbergová, Z., Oftedal, T.F., Ovchinnikov, K.V., Thiyagarajah, T., Rebroš, M., Diep, D.B. (2022). Identification of a Novel Two-Peptide Lantibiotic from Vagococcus fluvialis. Microbiol Spectrum e00954-22.
Oftedal T.F. (2021). Ubericin K, a New Pore-Forming Bacteriocin Targeting mannose-PTS. Poster presentasjon: IBA Annual Meeting, November 1-2, Oslo, Norge.
Oftedal T.F., Ovchinnikov K.V., Hestad K.A., Goldbeck O., Porcellato D., Narvhus J., Riedel C.U., Kjos M., Diep D.B. (2021). Ubericin K, a New Pore-Forming Bacteriocin Targeting mannose-PTS. Microbiology Spectrum 0:e00299-21.
Oftedal T.F. (2019). Co-immunoprecipitation with the Multi-Peptide Bacteriocin GarKS Immunity Protein. Masteroppave tilgjengelig: https://nmbu.brage.unit.no hdl:11250/2606410.
Undervisning
Hovedveileder av masterstudenter:
Medveileder av masterstudenter:
- Maren Angermo
- Even A. Haslund
- Anne-Line Bakke
- Maren Sofie Foss Gulliksen
- Kristine Kippersund Brokstad
- Ingvild Andrea Liaset Røren
- Aurora Tamburstuen Slåen
- Kai Arne Hestad
- Thasanth Thiyagarajah
Annen veiledning:
- Anaïs Rogowsky
- Zuzana Rosenbergová
Involvert som hjelpelærer i Molekylærbiologi (BIO210) and Laboratorieøvelser i Molekylærbiologi (BIO211).
- BIO211, 2022: hjelpelærer i laboratoriearbeid og foreleser
- BIO211, 2021: hjelpelærer i laboratoriearbeid
- BIO211, 2020: filming, redigering og utføring av nettbasert laboratoriekurs.
- BIO210, 2019: hjelpelærer i kollokvier.
Annen undervisning:
- Næringsmiddelmikrobiologi (MVI220), 2020: bioinformatics lecture.
- Næringsmiddelmikrobiologi (MVI220), 2021: laboratory course teaching assistant
- Næringsmiddelmikrobiologi (MVI220), 2022: laboratory course teaching assistant
- Biokjemi (KJB200), 2018: colloquium teaching.
- Introduksjon til Bioteknologi og Kjemi (BIO101)