Thomas Oftedal

• Molecular Biology
• Biochemistry
• Bioinformatics
• Molecular Dynamics
• Programming

Academic profile and publications

Oftedal, T.F., Løvdal, T., Kjos, M. (2025). The phage shock protein response of Listeria monocytogenes influences tolerance to the multipeptide bacteriocin garvicin KS. bioRxiv. [PREPRINT].

Arbulu, S., Oftedal, F. F., Kjos, M. (2025). Transcriptomic response in planktonic and biofilm-associated cells of Streptococcus mutans treated with sublethal concentrations of chlorhexidine. FEMS Microbiology Letters.

Kranjec, C., Oftedal, T. F., Ovchinnikov, K. V., da Silva Duarte, V., Hermansen, S., Kaus-Drobek, M., Sabała, I., Porcellato, D., Carlsen, H., & Kjos, M. (2025). An antibiotic-free antimicrobial combination of bacteriocins and a peptidoglycan hydrolase: in vitro and in vivo assessment of its efficacy. Applied and Environmental Microbiology.

Oftedal, T.F., Diep, D. B., Kjos, M. (2024). Design of Novel Saposin-like Bacteriocins Using a Hybrid Approach. Probiotics and Antimicrobial Proteins.

Wolden R, Ovchinnikov KV, Venter HJ, Oftedal TF, Diep DB, Cavanagh JP. (2023). The novel bacteriocin romsacin from Staphylococcus haemolyticus inhibits Gram-positive WHO priority pathogens. Microbiology Spectrum 11(6): e00869-23.

Oftedal, T.F. (2023) Bacteriocins: from discovery to characterization and applications. Doctoral thesis available at: https://hdl.handle.net/11250/3098644

Oftedal, T. F. (2023). Design of Novel Saposin-like Bacteriocins with Antimicrobial Acitivity using a Hybrid Approach. Poster presentation: IBA Annual Meeting, October 9-10, Clarion Hotel Bjørvika, Oslo, Norway.

Oftedal, T. F. & Diep, D. B. (2023). Flow cytometric detection of vancomycin-resistant Enterococcus faecium in urine using fluorescently labelled enterocin K1. Sci Rep 13, 10930.

Oftedal, T.F. (2023). Detection of E. faecium using the specific interaction of a bacteriocin EntK1 with its receptor. Oral presentation at: Bacteriocin International Conference 2023, June 19-21, Lille, France.

Oftedal, T. F. (2022). Identification of a Novel Two-Peptide Lantibiotic from Vagococcus fluvialis. Poster presentation at: 7th International Symposium on Antimicrobial Peptides - AMP2022, November 7-9, Institut Pasteur, Paris, France.

Kristensen, S. S., Oftedal, T. F., Røhr, Å. K., Eijsink, V. G. H., Mathiesen, G., & Diep, D. B. (2022). The extracellular domain of site-2-metalloprotease RseP is important for sensitivity to bacteriocin EntK1. J. Biol. Chem. In Press. 102593.

Ovchinnikov, K. V., Oftedal, T. F., Reich, S. J., Bar, N. S., Holo, H., Skaugen, M., Riedel, C. U. and Diep, D. B. (2022). Genome-assisted Identification, Purification, and Characterization of Bacteriocins. Bio-protocol 12(14): e4477.  

Oftedal, T.F. (2022). Genome-assisted identification, purification and characterization of a novel bacteriocin. Oral presentation at: International Scientific Conference on Probiotics, Prebiotics, Gut Microbiota and Health, June 27-30, Bratislava, Slovakia.

Rosenbergová, Z., Oftedal, T.F., Ovchinnikov, K.V., Thiyagarajah, T., Rebroš, M., Diep, D.B. (2022). Identification of a Novel Two-Peptide Lantibiotic from Vagococcus fluvialis. Microbiol Spectrum e00954-22.

Oftedal T.F. (2021). Ubericin K, a New Pore-Forming Bacteriocin Targeting mannose-PTS. Poster presented at: IBA Annual Meeting, November 1-2, Oslo, Norway.

Oftedal T.F., Ovchinnikov K.V., Hestad K.A., Goldbeck O., Porcellato D., Narvhus J., Riedel C.U., Kjos M., Diep D.B. (2021). Ubericin K, a New Pore-Forming Bacteriocin Targeting mannose-PTS. Microbiology Spectrum 0:e00299-21.

Oftedal T.F. (2019). Co-immunoprecipitation with the Multi-Peptide Bacteriocin GarKS Immunity Protein. Master's thesis submitted to: https://nmbu.brage.unit.no hdl:11250/2606410.