The MEMO group applies interdisciplinary approaches to study the microbiomes inhabiting digestive systems, including important production animals (cows, pigs and salmon), wild herbivores (moose, reindeer), environmental sediments as well as us! We also on occasion delve into commercial biogas reactors that recycle municipal waste in Scandinavia.
Key MEMO research interests are using multi-omic tools to deconvolute the intimate genetic and physiological relationship between the host animal, its environment and its microbiome. We combine analytical metadata, biochemistry and growth experiments with metabolic reconstructions of population genomes to visualize flow of metabolites in complex microbiomes, and have used temporal meta-omics and co-expression network analysis to interpret synergistic interactions between fiber-degrading and methanogenic microbial populations. We are now seeking to expand these approaches to envelop additional “molecular layers” from the animal holobiont (i.e. host transcriptome and proteome), a concept otherwise known as “holo-omics”.
MEMO is structured as a focus group and our MEMO members are formally integrated accross several faculties and research groups at NMBU, including the Nutrition group and CIGENE at BIOVIT. In addition, MEMO members work in concert at KBM with the PEP group to faciliate the coupling of high-resolution omics with in-depth biochemistry, and the BIAS group for bioinformatics. We are funded by the European Research Council (ERC Starting Grant), The Research Council of Norway (FRIMEDBIO and HAVBRUK), The BlueBio Co-fund (ERA-Net), The European Commission (Horizon 2020) and the Novo Nordisk Foundation(NNF).