European Commision - H2020 ICT-30-2017 - Photonics KET 2017
Project number: 780598
Period covered - start date: 1/1/2018
Period covered - end date: 30/6/2021
Project's coordinator: Gabriela S. Lorite Yrjänä, University of Oulu
NMBU coordinator: Achim Kohler
The MIRACLE project joins 13 European partners from 6 countries and is coordinated by the University of Oulu. MIRACLE will implement and demonstrate an easy-to-operate mid-infrared (MIR) imaging-probe to be used during arthroscopic surgery enabling in-depth diagnosis of articular cartilage. In current clinical practice, the articular cartilage assessment during arthroscopic surgery is solely based by visual inspection and manual probing of the cartilage tissue, which is highly subjective and of poor repeatability. MIRACLE will enable the in vivo accurate evaluation of the biochemical status and composition of articular cartilage, thus assisting the orthopedic surgeon in more objective decision making during the surgery.
BioSpec group at NMBU contributes to the project with multivariate data analysis and spectral pre-processing, for the establishment of multivariate discriminant models to distinguish between healthy and unhealthy tissue conditions.
Literature:
Rehman H.U., Tafintseva V., Zimmermann B., Solheim J., Virtanen V., Shaikh R., Nippolainen E., Afara I., Saarakkala S, Rieppo L., Krebs P., Fomina P., Mizaikoff B., Kohler A.
Preclassification of broadband and sparse infrared data by multiplicative signal correction approach.
Molecules 27 (2022) 2298
Virtanen V., Tafintseva V., Shaikh R., Nippolainen E., Haas J., Afara I., Töyräs J., Kröger H., Solheim J., Zimmermann B., Kohler A., Mizaikoff B., Finnilä M., Rieppo L., Saarakkala S.
Infrared spectroscopy is suitable for objective assessment of articular cartilage health
Osteoarthritis and Cartilage Open 4 (2022) 100250
Tafintseva V., Lintvedt T.A., Solheim J., Zimmermann B., Rehman H.U., Virtanen V., Shaikh R., Nippolainen E., Afara I., Saarakkala S, Rieppo L., Krebs P., Fomina P., Mizaikoff B., Kohler A.
Preprocessing Strategies for Sparse Infrared Spectroscopy: A Case Study on Cartilage Diagnostics.
Molecules 27 (2022) 873
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This project received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 780598.
The project is an initiative of the Photonics Public Private Partnership.
