Dag Anders Brede

Professor

Seksjon for miljøkjemi

I am a professor at the Isotopelaboratory (MINA/NMBU) working on radioecology and ecotoxicology. My main interests are to study effects of environmental toxins such as radionuclides, heavy metal toxicity and nanoparticles using model organisms such as C. elegans to investigate molecular toxicity mechanisms. I have a particular interest in uptake, accumulation and excretion (toxicokinetics) of environmental toxins. We use ICP-MS and Synchrotron radioation XRF to assess biodistribution in these model organisms.

I also study toxic effects of ionizing radiation with focus on environmental protection. Sensitivity to ionizing radiation (Radiosensitivity) varies greatly between species. In addition, certain developmental stages or cell types are more vulnerable to ionizing radiation. I aim to identify traits that determine the radiosensitivity of different species with emphasis on damage, defense and repair.

Fagfelt
- Radioøkologi
- Økotoksikologi
- Miljøkjemi
Publikasjoner
Forskerprofil med publikasjoner i vitenarkivet
Undervisning
FMI210 Generell miljøtoksikologi
Emnet gir en innføring i sentrale prinsipper for toksikologi og økotoksikologi. Emnet gir kunnskap om de viktigste gruppene av miljøgifter og virkningsmekanisme av disse. Dette inkluderer opptak, fordeling, metabolisme og utskillelse av giftige stoffer i organismer. Emnet gir grunnleggende kunnskap om hvordan ulike miljøgifters interaksjon med biomolekyler fører til toksiske effekter. Gjennom laboratorieøvelser vil studentene få praktisk erfaring med toksisitetstesting på molekylært, cellulært, organisme og populasjons-nivå. Studentene lærer å analysere, tolke og rapportere vitenskapelige data. Miljøtoksikologi dekker aspekter med relevans for både human toksikologi og økotoksikologi.
https://www.nmbu.no/emne/fmi210
In English
FMI210 Principal Environmental Toxicology
The course provides an introduction to central principles of toxicology and ecotoxicology. The subject provides knowledge about the most important groups of environmental toxins and their mechanisms of action. This includes the uptake, distribution, metabolism and excretion of toxic substances in organisms. The subject provides basic knowledge about how various environmental toxins interact with biomolecules leading to toxic effects. Through laboratory exercises, students will gain practical experience with toxicity testing at molecular, cellular, organism and population level. Students learn to analyse, interpret and report scientific data. Environmental toxicology covers aspects with relevance to both human toxicology and ecotoxicology.