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Read our peer-reviewed scientific publications from 2010 onwards.

You may also view selected publications before 2010


Last Updated: May 28, 2020


Ecological processes affecting long-term eukaryote and prokaryote biofilm persistence in nitrogen removal from sewage. Angell IL, Bergaust L, Hanssen JF, Aasen EM, Rudi K. Genes (Basel). 2020 Apr 20; 11(4):449. doi: 10.3390/genes11040449.

Author correction: mud volcanoes and the presence of PAHs. Remizovschi A, Carpa R, Forray FL, Chiriac C, Roba CA, Beldean-Galea S, Andrei AȘ, Szekeres E, Baricz A, Lupan I, Rudi K, Coman C. Sci Rep. 2020 Apr 15; 10(1):6668. doi: 10.1038/s41598-020-62513-x.

Maternal use of nicotine products and breastfeeding 3 months postpartum. Nordhagen LS, Kreyberg I, Eline S Bains K, Carlsen KH, Glavin K, Skjerven HO, Småstuen MC, Hilde K, Nordlund B, Vettukattil R, Hedlin G, Granum B, Jonassen CM, Gudmundsdóttir HK, Haugen G, Maria Rehbinder E, Söderhäll C, Cathrine Staff A, Lødrup Carlsen KC; PreventADALL study group. Acta Paediatr. 2020 Apr 10. doi: 10.1111/apa.15299.

Preformulation studies on novel garvicin KS peptides for topical applications. Thapa RK, Winther-Larsen HC, Diep DB, Tønnesen HH. Eur J Pharm Sci. 2020 Apr 5:105333. doi: 10.1016/j.ejps.2020.105333.

Total synthesis of the enantiomers of thioridazine. Antonsen S, Monsen E, Ovchinnikov K, Nolsøe Jens MJ, Ekeberg D, Kristiansen J, Diep D, Stenstrøm Y; SynOpen 2020; 04(01): 12-16 doi: 10.1055/s-0039-1690834

Engineering Lactococcus lactis for increased Vitamin K2 production. Bøe CA, Holo H. Front Bioeng Biotechnol. 2020 Mar 18; 8:191. doi: 10.3389/fbioe.2020.00191. eCollection 2020.

Biochemical, genetic and transcriptional characterization of multibacteriocin production by the anti-pneumococcal dairy strain Streptococcus infantarius LP90. Campanero C, Muñoz-Atienza E, Diep DB, Feito J, Arbulu S, Del Campo R, Nes IF, Hernández PE, Herranz C, Cintas LM. PLoS One. 2020 Mar 5; 15(3):e0229417. doi: 10.1371/journal.pone.0229417. eCollection 2020.

Skin emollient and early complementary feeding to prevent infant atopic dermatitis (PreventADALL): a factorial, multicentre, cluster-randomised trial. Skjerven HO, Rehbinder EM, Vettukattil R, LeBlanc M, Granum B, Haugen G, Hedlin G, Landrø L, Marsland BJ, Rudi K, Sjøborg KD, Söderhäll C, Staff AC, Carlsen KH, Asarnoj A, Bains KES, Carlsen OCL, Endre KMA, Granlund PA, Hermansen JU, Gudmundsdóttir HK, Hilde K, Håland G, Kreyberg I, Olsen IC, Mägi CO, Nordhagen LS, Saunders CM, Skrindo I, Tedner SG, Værnesbranden MR, Wiik J, Jonassen CM, Nordlund B, Carlsen KCL. Lancet. 2020 Mar 21; 395(10228):951-961. doi: 10.1016/S0140-6736(19)32983-6. Epub 2020 Feb 19.

Culture dependent and independent analyses suggest a low level of sharing of endospore-forming species between mothers and their children. Avershina E, Larsen MG, Aspholm M, Lindback T, Storrø O, Øien T, Johnsen R, Rudi K. Sci Rep. 2020 Feb 4; 10(1):1832. doi: 10.1038/s41598-020-58858-y.

Pre- and post-race intestinal microbiota in long-distance sled dogs and associations with performance. Tysnes KR, Angell IL, Fjellanger I, Larsen SD, Søfteland SR, Robertson LJ, Skancke E, Rudi K. Animals (Basel). 2020 Jan 25; 10(2):204. doi: 10.3390/ani10020204.

Mud volcanoes and the presence of PAHs. Remizovschi A, Carpa R, Forray FL, Chiriac C, Roba CA, Beldean-Galea S, Andrei AȘ, Szekeres E, Baricz A, Lupan I, Rudi K, Coman C. Sci Rep. 2020 Jan 27; 10(1):1253. doi: 10.1038/s41598-020-58282-2.


Food and nutrient intake and adherence to dietary recommendations during pregnancy: a Nordic mother-child population-based cohort. Saunders CM, Rehbinder EM, Carlsen KCL, Gudbrandsgard M, Carlsen KH, Haugen G, Hedlin G, Jonassen CM, Sjøborg KD, Landrø L, Nordlund B, Rudi K, O Skjerven H, Söderhäll C, Staff AC, Vettukattil R, Carlsen MH. Food Nutr Res. 2019 Dec 20; 63. doi: 10.29219/fnr.v63.3676. eCollection 2019.

Topical antimicrobial peptide formulations for wound healing: current developments and future prospects. Thapa RK, Diep DB, Tønnesen HH. Acta Biomater. 2020 Feb; 103:52-67. doi: 10.1016/j.actbio.2019.12.025. Epub 2019 Dec 23.

Bacteriocin production and distribution of bacteriocin-encoding genes in enterococci from dogs. Kubašová I, Diep DB, Ovchinnikov KV, Lauková A, Strompfová V. Int J Antimicrob Agents. 2020 Feb; 55(2):105859. doi: 10.1016/j.ijantimicag.2019.11.016.

Use of fecal slurry cultures to study in vitro effects of bacteriocins on the gut bacterial populations of infants. Umu ÖCO, Gueimonde M, Oostindjer M, Ovchinnikov KV, de Los Reyes-Gavilán CG, Arbulu S, Hernández PE, Martínez B, Diep DB, Salazar N. Probiotics Antimicrob Proteins. 2019 Dec 1. doi: 10.1007/s12602-019-09614-w. Online ahead of print.

The increasing issue of vancomycin-resistant enterococci and the bacteriocin solution. Reinseth IS, Ovchinnikov KV, Tønnesen HH, Carlsen H, Diep DB. Probiotics Antimicrob Proteins. 2019 Nov 22. doi: 10.1007/s12602-019-09618-6.

Predicting skin barrier dysfunction and atopic dermatitis in early infancy. Rehbinder EM, Advocaat Endre KM, Lødrup Carlsen KC, Asarnoj A, Stensby Bains KE, Berents TL, Carlsen KH, Gudmundsdóttir HK, Haugen G, Hedlin G, Kreyberg I, Nordhagen LS, Nordlund B, Saunders CM, Sandvik L, Skjerven HO, Söderhäll C, Staff AC, Vettukattil R, Værnesbranden MR, Landrø L; study group, Carlsen MH, Lødrup Carlsen OC, Granlund PA, Granum B, Götberg S, Hilde K, Jonassen CM, Nygaard UC, Rudi K, Skrindo I, Sjøborg K, Tedner SG, Wiik J, Winger AJ. J Allergy Clin Immunol Pract. 2020 Feb; 8(2):664-673.e5. doi: 10.1016/j.jaip.2019.09.014. Epub 2019 Sep 27.

Maternal and paternal atopic dermatitis and risk of atopic dermatitis during early infancy in girls and boys. Endre KMA, Rehbinder EM, Carlsen KL, Carlsen KH, Gjersvik P, Hedlin G, Jonassen CM, LeBlanc M, Nordlund B, Skjerven HO, Staff AC, Söderhäll C, Vettukattil R, Landrø L; study group. J Allergy Clin Immunol Pract. 2020 Jan; 8(1):416-418.e2. doi: 10.1016/j.jaip.2019.06.039. Epub 2019 Jul 15.

Experimental support for multidrug resistance transfer potential in the preterm infant gut microbiota. Hagbø M, Ravi A, Angell IL, Sunde M, Ludvigsen J, Diep DB, Foley SL, Vento M, Collado MC, Perez-Martinez G, Rudi K. Pediatr Res. 2019 Jul 1. doi: 10.1038/s41390-019-0491-8.

Microbial ecological processes in MBBR biofilms for biological phosphorus removal from wastewater. Rudi K, Goa IA, Saltnes T, Sørensen G, Angell IL, Eikås S. Water Sci Technol. 2019 Apr; 79(8):1467-1473. doi: 10.2166/wst.2019.149.

Unprecedented diversity of Lactococcal Group 936 bacteriophages revealed by amplicon sequencing of the portal protein gene. Frantzen CA, Holo H. Viruses. 2019 May 16; 11(5):443. doi: 10.3390/v11050443.

Association between diet and rumen microbiota in wild roe deer. Wilson R, Østbye K, Angell IL, Rudi K. FEMS Microbiol Lett. 2019 Mar 1; 366(6):fnz060. doi: 10.1093/femsle/fnz060.

Over 2000-fold increased production of the leaderless bacteriocin Garvicin KS by increasing gene dose and optimization of culture conditions. Telke AA, Ovchinnikov KV, Vuoristo KS, Mathiesen G, Thorstensen T, Diep DB. Front Microbiol. 2019 Mar 5; 10:389. doi: 10.3389/fmicb.2019.00389. eCollection 2019.

Liquid array diagnostics: a novel method for rapid detection of microbial communities in single-tube multiplex reactions. Hiseni P, Wilson RC, Storrø O, Johnsen R, Øien T, Rudi K.Biotechniques. 2019 Mar; 66(3):143-149. doi: 10.2144/btn-2018-0134.

Exploring the brine microbiota of a traditional Norwegian fermented fish product (rakfisk) from six different producers during two consecutive seasonal productions. Bjerke GA, Rudi K, Avershina E, Moen B, Blom H, Axelsson L.Foods. 2019 Feb 14; 8(2):72. doi: 10.3390/foods8020072.


Intracellular pHluorin as sensor for easy assessment of bacteriocin-induced membrane-damage in Listeria monocytogenes. Crauwels P, Schäfer L, Weixler D, Bar NS, Diep DB, Riedel CU, Seibold GM. Front Microbiol. 2018 Dec 11; 9:3038. doi: 10.3389/fmicb.2018.03038. eCollection 2018.

The extracellular loop of Man-PTS subunit IID is responsible for the sensitivity of Lactococcus garvieae to garvicins A, B and C. Tymoszewska A, Diep DB, Aleksandrzak-Piekarczyk T. Sci Rep. 2018 Oct 25; 8(1):15790. doi: 10.1038/s41598-018-34087-2.

Allergen immunization induces major changes in microbiota composition and short-chain fatty acid production in different gut segments in a mouse model of lupine food allergy. Andreassen M, Rudi K, Angell IL, Dirven H, Nygaard UC. Int Arch Allergy Immunol. 2018; 177(4):311-323. doi: 10.1159/000492006. Epub 2018 Sep 21.

Is amniotic fluid of women with uncomplicated term pregnancies free of bacteria? Rehbinder EM, Lødrup Carlsen KC, Staff AC, Angell IL, Landrø L, Hilde K, Gaustad P, Rudi K. Am J Obstet Gynecol. 2018 Sep; 219(3):289.e1-289.e12. doi: 10.1016/j.ajog.2018.05.028. Epub 2018 May 29.

Low maternal microbiota sharing across gut, breast milk and vagina, as revealed by 16S rRNA gene and reduced metagenomic sequencing. Avershina E, Angell IL, Simpson M, Storrø O, Øien T, Johnsen R, Rudi K. Genes (Basel). 2018 May 1; 9(5):231. doi: 10.3390/genes9050231.

Impact of HIV and type 2 diabetes on gut microbiota diversity, tryptophan catabolism and endothelial dysfunction. Hoel H, Hove-Skovsgaard M, Hov JR, Gaardbo JC, Holm K, Kummen M, Rudi K, Nwosu F, Valeur J, Gelpi M, Seljeflot I, Ueland PM, Gerstoft J, Ullum H, Aukrust P, Nielsen SD, Trøseid M. Sci Rep. 2018 Apr 30;8(1):6725. doi: 10.1038/s41598-018-25168-3.

Preventing atopic dermatitis and ALLergies in children-the PreventADALL study. Lødrup Carlsen KC, Rehbinder EM, Skjerven HO, Carlsen MH, Fatnes TA, Fugelli P, Granum B, Haugen G, Hedlin G, Jonassen CM, Landrø L, Lunde J, Marsland BJ, Nordlund B, Rudi K, Sjøborg K, Söderhäll C, Staff AC, Vettukattil R, Carlsen KH; study group. Allergy. 2018 Oct; 73(10):2063-2070. doi: 10.1111/all.13468. Epub 2018 Jun 19.

Addressing the diversity of the honeybee gut symbiont Gilliamella: description of Gilliamella apis sp. nov., isolated from the gut of honeybees (Apis mellifera). Ludvigsen J, Porcellato D, Amdam GV, Rudi K. Int J Syst Evol Microbiol. 2018 May; 68(5):1762-1770. doi: 10.1099/ijsem.0.002749. Epub 2018 Apr 6.

Earthworms are associated with subpopulations of Gammaproteobacteria irrespective of the total soil microbiota composition and stability. Fjøsne T, Myromslien FD, Wilson RC, Rudi K. FEMS Microbiol Lett. 2018 May 1; 365(9). doi: 10.1093/femsle/fny071.

Detection and characterization of streptomycin resistance (strA-strB) in a honeybee gut symbiont (Snodgrassella alvi) and the associated risk of antibiotic resistance transfer. Ludvigsen J, Amdam GV, Rudi K, L'Abée-Lund TM. Microb Ecol. 2018 Oct; 76(3):588-591. doi: 10.1007/s00248-018-1171-7. Epub 2018 Mar 8.

Comparison of reduced metagenome and 16S rRNA gene sequencing for determination of genetic diversity and mother-child overlap of the gut associated microbiota. Ravi A, Avershina E, Angell IL, Ludvigsen J, Manohar P, Padmanaban S, Nachimuthu R, Snipen L, Rudi K. J Microbiol Methods. 2018 Jun; 149:44-52. doi: 10.1016/j.mimet.2018.02.016. Epub 2018 Mar 1.

Investigating antibiotics, antibiotic resistance genes, and microbial contaminants in groundwater in relation to the proximity of urban areas. Szekeres E, Chiriac CM, Baricz A, Szőke-Nagy T, Lung I, Soran ML, Rudi K, Dragos N, Coman C. Environ Pollut. 2018 May; 236:734-744. doi: 10.1016/j.envpol.2018.01.107. Epub 2018 Feb 15.


Breastfeeding-associated microbiota in human milk following supplementation with Lactobacillus rhamnosus GG, Lactobacillus acidophilus La-5, and Bifidobacterium animalis ssp. lactis Bb-12. Simpson MR, Avershina E, Storrø O, Johnsen R, Rudi K, Øien T. J Dairy Sci. 2018 Feb; 101(2):889-899. doi: 10.3168/jds.2017-13411. Epub 2017 Dec 14.

Diversity of vaginal microbiota increases by the time of labor onset. Avershina E, Slangsvold S, Simpson MR, Storrø O, Johnsen R, Øien T, Rudi K. Sci Rep. 2017 Dec 14; 7(1):17558. doi: 10.1038/s41598-017-17972-0.

Lactococcus lactis diversity in undefined mixed dairy starter cultures as revealed by comparative genome analyses and targeted amplicon sequencing of epsD. Frantzen CA, Kleppen HP, Holo H. Appl Environ Microbiol. 2018 Jan 17; 84(3):e02199-17. doi: 10.1128/AEM.02199-17. Print 2018 Feb 1.

iNOS- and NOX1-dependent ROS production maintains bacterial homeostasis in the ileum of mice. Matziouridou C, Rocha SDC, Haabeth OA, Rudi K, Carlsen H, Kielland A. Mucosal Immunol. 2018 May; 11(3):774-784. doi: 10.1038/mi.2017.106. Epub 2017 Dec 6.

Functional bowel disorders are associated with a central immune activation. Farup PG, Ueland T, Rudi K, Lydersen S, Hestad K. Gastroenterol Res Pract. 2017; 2017:1642912. doi: 10.1155/2017/1642912. Epub 2017 Oct 23.

Transmission and persistence of IncF conjugative plasmids in the gut microbiota of full-term infants. Ravi A, Valdés-Varela L, Gueimonde M, Rudi K. FEMS Microbiol Ecol. 2018 Jan 1; 94(1). doi: 10.1093/femsec/fix158.

Stable core gut microbiota across the freshwater-to-saltwater transition for farmed Atlantic salmon. Rudi K, Angell IL, Pope PB, Vik JO, Sandve SR, Snipen LG. Appl Environ Microbiol. 2018 Jan 2; 84(2):e01974-17. doi: 10.1128/AEM.01974-17. Print 2018 Jan 15.

Geographically widespread honeybee-gut symbiont subgroups show locally distinct antibiotic-resistant patterns. Ludvigsen J, Porcellato D, L'Abée-Lund TM, Amdam GV, Rudi K. Mol Ecol. 2017 Dec; 26(23):6590-6607. doi: 10.1111/mec.14392. Epub 2017 Nov 23.

Synergistic antimicrobial activity between the broad spectrum bacteriocin Garvicin KS and Nisin, Farnesol and Polymyxin B against gram-positive and gram-negative bacteria. Chi H, Holo H. Curr Microbiol. 2018 Mar; 75(3):272-277. doi: 10.1007/s00284-017-1375-y. Epub 2017 Oct 20.

Modulation of the gut microbiota by prebiotic fibres and bacteriocins. Umu ÖCO, Rudi K, Diep DB. Microb Ecol Health Dis. 2017 Jan 1; 28(1):1348886. doi: 10.1080/16512235.2017.1348886. eCollection 2017.

The non-lantibiotic bacteriocin Garvicin Q targets Man-PTS in a broad spectrum of sensitive bacterial genera. Tymoszewska A, Diep DB, Wirtek P, Aleksandrzak-Piekarczyk T. Sci Rep. 2017 Aug 21; 7(1):8359. doi: 10.1038/s41598-017-09102-7.

A method to assess bacteriocin effects on the gut microbiota of mice. Bäuerl C, Umu ÖCO, Hernandez PE, Diep DB, Pérez-Martínez G. J Vis Exp. 2017 Jul 25; (125):56053. doi: 10.3791/56053.

The leaderless bacteriocin Enterocin K1 is highly potent against Enterococcus faecium: a study on structure, target spectrum and receptor. Ovchinnikov KV, Kristiansen PE, Straume D, Jensen MS, Aleksandrzak-Piekarczyk T, Nes IF, Diep DB. Front Microbiol. 2017 May 3; 8:774. doi: 10.3389/fmicb.2017.00774. eCollection 2017.

The prevalence of Listeria monocytogenes and Staphylococcus aureus and their virulence genes in bulk tank milk in Kosovo. Mehmeti I, Bytyqi H, Muji S, Nes IF, Diep DB. J Infect Dev Ctries. 2017 Mar 31; 11(3):247-254. doi: 10.3855/jidc.8256.

Genomic characterization of dairy associated leuconostoc species and diversity of leuconostocs in undefined mixed mesophilic starter cultures. Frantzen CA, Kot W, Pedersen TB, Ardö YM, Broadbent JR, Neve H, Hansen LH, Dal Bello F, Østlie HM, Kleppen HP, Vogensen FK, Holo H. Front Microbiol. 2017 Feb 3; 8:132. doi: 10.3389/fmicb.2017.00132. eCollection 2017.


Antimicrobial resistance levels amongst staphylococci isolated from clinical cases of bovine mastitis in Kosovo. Mehmeti I, Behluli B, Mestani M, Ademi A, Nes IF, Diep DB. J Infect Dev Ctries. 2016 Oct 31; 10(10):1081-1087. doi: 10.3855/jidc.7912.

The potential of class II bacteriocins to modify gut microbiota to improve host health. Umu ÖC, Bäuerl C, Oostindjer M, Pope PB, Hernández PE, Pérez-Martínez G, Diep DB. PLoS One. 2016 Oct 3; 11(10):e0164036. doi: 10.1371/journal.pone.0164036. eCollection 2016.

Draft genome sequence of the bacteriocinogenic strain Enterococcus faecalis DBH18, isolated from mallard ducks (Anas platyrhynchos). Arbulu S, Jimenez JJ, Borrero J, Sánchez J, Frantzen C, Herranz C, Nes IF, Cintas LM, Diep DB, Hernández PE. Genome Announc. 2016 Jul 14; 4(4):e00663-16. doi: 10.1128/genomeA.00663-16.

LsbB bacteriocin interacts with the third transmembrane domain of the YvjB receptor. Miljkovic M, Uzelac G, Mirkovic N, Devescovi G, Diep DB, Venturi V, Kojic M. Appl Environ Microbiol. 2016 Aug 15; 82(17):5364-74. doi: 10.1128/AEM.01293-16. Print 2016 Sep 1.

Novel group of leaderless multipeptide bacteriocins from gram-positive bacteria. Ovchinnikov KV, Chi H, Mehmeti I, Holo H, Nes IF, Diep DB. Appl Environ Microbiol. 2016 Aug 15; 82(17):5216-24. doi: 10.1128/AEM.01094-16. Print 2016 Sep 1.

Draft genome sequence of the bacteriocin-producing strain Enterococcus faecium M3K31, isolated from griffon vultures (Gyps fulvus subsp. fulvus). Arbulu S, Frantzen C, Lohans CT, Cintas LM, Herranz C, Holo H, Diep DB, Vederas JC, Hernández PE. Genome Announc. 2016 Mar 24; 4(2):e00055-16. doi: 10.1128/genomeA.00055-16.

The interaction between Staphylococcus aureus SdrD and desmoglein 1 is important for adhesion to host cells. Askarian F, Ajayi C, Hanssen AM, van Sorge NM, Pettersen I, Diep DB, Sollid JU, Johannessen M. Sci Rep. 2016 Feb 29; 6:22134. doi: 10.1038/srep22134.

Lactococcus lactis LMG2081 produces two bacteriocins, a nonlantibiotic and a novel lantibiotic. Mirkovic N, Polovic N, Vukotic G, Jovcic B, Miljkovic M, Radulovic Z, Diep DB, Kojic M. Appl Environ Microbiol. 2016 Apr 4; 82(8):2555-2562. doi: 10.1128/AEM.03988-15. Print 2016 Apr.


Efficient inactivation of multi-antibiotics resistant nosocomial Enterococci by purified Hiracin bacteriocin. Hassan M, Brede DA, Diep DB, Nes IF, Lotfipour F, Hojabri Z. Adv Pharm Bull. 2015 Sep; 5(3):393-401. doi: 10.15171/apb.2015.054. Epub 2015 Sep 19.

Cloning strategies for heterologous expression of the bacteriocin enterocin A by Lactobacillus sakei Lb790, Lb. plantarum NC8 and Lb. casei CECT475. Jiménez JJ, Diep DB, Borrero J, Gútiez L, Arbulu S, Nes IF, Herranz C, Cintas LM, Hernández PE. Microb Cell Fact. 2015 Oct 15; 14:166. doi: 10.1186/s12934-015-0346-x.

Resistant starch diet induces change in the swine microbiome and a predominance of beneficial bacterial populations. Umu ÖC, Frank JA, Fangel JU, Oostindjer M, da Silva CS, Bolhuis EJ, Bosch G, Willats WG, Pope PB, Diep DB. Microbiome. 2015 Apr 16; 3:16. doi: 10.1186/s40168-015-0078-5. eCollection 2015.

Draft genome sequence of Lactobacillus kunkeei AR114 isolated from honey bee gut. Porcellato D, Frantzen C, Rangberg A, Umu OC, Gabrielsen C, Nes IF, Amdam GV, Diep DB. Genome Announc. 2015 Mar 19; 3(2):e00144-15. doi: 10.1128/genomeA.00144-15.

A genomic virulence reference map of Enterococcus faecalis reveals an important contribution of phage03-like elements in nosocomial genetic lineages to pathogenicity in a Caenorhabditis elegans infection model.  La Rosa SL, Snipen LG, Murray BE, Willems RJ, Gilmore MS, Diep DB, Nes IF, Brede DA. Infect Immun. 2015 May; 83(5):2156-67. doi: 10.1128/IAI.02801-14. Epub 2015 Mar 16.

The fsr quorum-sensing system and cognate gelatinase orchestrate the expression and processing of proprotein EF_1097 into the mature antimicrobial peptide enterocin O16. Dundar H, Brede DA, La Rosa SL, El-Gendy AO, Diep DB, Nes IF. J Bacteriol. 2015 Jul; 197(13):2112-2121. doi: 10.1128/JB.02513-14. Epub 2015 Mar 2.

Bioluminescence based biosensors for quantitative detection of enterococcal peptide-pheromone activity reveal inter-strain telesensing in vivo during polymicrobial systemic infection. La Rosa SL, Solheim M, Diep DB, Nes IF, Brede DA. Sci Rep. 2015 Feb 9; 5:8339. doi: 10.1038/srep08339.

EF0176 and EF0177 from Enterococcus faecalis V583 are substrate-binding lipoproteins involved in ABC transporter mediated ribonucleoside uptake. Karlskås IL, Saleihan Z, Holo H, Mathiesen G, Eijsink VG. Microbiology. 2015 Apr; 161(Pt 4):754-64. doi: 10.1099/mic.0.000045. Epub 2015 Jan 29.

The paratransgenic potential of Lactobacillus kunkeei in the honey bee Apis mellifera. Rangberg A, Mathiesen G, Amdam GV, Diep DB. Benef Microbes. 2015; 6(4):513-23. doi: 10.3920/BM2014.0115. Epub 2015 Feb 12.


Using a genome-scale metabolic model of Enterococcus faecalis V583 to assess amino acid uptake and its impact on central metabolism. Veith N, Solheim M, van Grinsven KW, Olivier BG, Levering J, Grosseholz R, Hugenholtz J, Holo H, Nes I, Teusink B, Kummer U. Appl Environ Microbiol. 2015 Mar; 81(5):1622-33. doi: 10.1128/AEM.03279-14. Epub 2014 Dec 19.

Circular bacteriocins: biosynthesis and mode of action. Gabrielsen C, Brede DA, Nes IF, Diep DB. Appl Environ Microbiol. 2014 Nov; 80(22):6854-62. doi: 10.1128/AEM.02284-14. Epub 2014 Aug 29.

Defining the structure and receptor binding domain of the leaderless bacteriocin LsbB. Ovchinnikov KV, Kristiansen PE, Uzelac G, Topisirovic L, Kojic M, Nissen-Meyer J, Nes IF, Diep DB. J Biol Chem. 2014 Aug 22; 289(34):23838-45. doi: 10.1074/jbc.M114.579698. Epub 2014 Jul 3.

Sensitivity to the two-peptide bacteriocin lactococcin G is dependent on UppP, an enzyme involved in cell-wall synthesis. Kjos M, Oppegård C, Diep DB, Nes IF, Veening JW, Nissen-Meyer J, Kristensen T. Mol Microbiol. 2014 Jun; 92(6):1177-87. doi: 10.1111/mmi.12632. Epub 2014 May 23.

Enterococcal bacteriocins and antimicrobial proteins that contribute to niche control. Ness IF, Diep DB, Ike Y. 2014 Feb 16. In: Gilmore MS, Clewell DB, Ike Y, Shankar N, editors. Enterococci: From Commensals to Leading Causes of Drug Resistant Infection [Internet]. Boston: Massachusetts Eye and Ear Infirmary; 2014–.

Functional genetic analysis of the GarML gene cluster in Lactococcus garvieae DCC43 gives new insights into circular bacteriocin biosynthesis. Gabrielsen C, Brede DA, Salehian Z, Nes IF, Diep DB. J Bacteriol. 2014 Mar; 196(5):911-9. doi: 10.1128/JB.01115-13. Epub 2013 Dec 13.


A Zn-dependent metallopeptidase is responsible for sensitivity to LsbB, a class II leaderless bacteriocin of Lactococcus lactis subsp. lactis BGMN1-5. Uzelac G, Kojic M, Lozo J, Aleksandrzak-Piekarczyk T, Gabrielsen C, Kristensen T, Nes IF, Diep DB, Topisirovic L.J Bacteriol. 2013 Dec;195(24):5614-21. doi: 10.1128/JB.00859-13. Epub 2013 Oct 11.

Potential applications of gut microbiota to control human physiology. Umu OC, Oostindjer M, Pope PB, Svihus B, Egelandsdal B, Nes IF, Diep DB.Antonie Van Leeuwenhoek. 2013 Nov;104(5):609-18. doi: 10.1007/s10482-013-0008-0. Epub 2013 Aug 23.

Cloning, production, and functional expression of the bacteriocin sakacin A (SakA) and two SakA-derived chimeras in lactic acid bacteria (LAB) and the yeasts Pichia pastoris and Kluyveromyces lactis. Jiménez JJ, Borrero J, Diep DB, Gútiez L, Nes IF, Herranz C, Cintas LM, Hernández PE.J Ind Microbiol Biotechnol. 2013 Sep;40(9):977-93. doi: 10.1007/s10295-013-1302-6. Epub 2013 Jun 22.

Enterococcus faecalis grows on ascorbic acid. Mehmeti I, Solheim M, Nes IF, Holo H.Appl Environ Microbiol. 2013 Aug;79(15):4756-8. doi: 10.1128/AEM.00228-13. Epub 2013 May 24.

In vivo assessment of growth and virulence gene expression during commensal and pathogenic lifestyles of luxABCDE-tagged Enterococcus faecalis strains in murine gastrointestinal and intravenous infection models. La Rosa SL, Casey PG, Hill C, Diep DB, Nes IF, Brede DA.Appl Environ Microbiol. 2013 Jul;79(13):3986-97. doi: 10.1128/AEM.00831-13. Epub 2013 Apr 19.


Genome sequence of the bacteriocin-producing strain Lactococcus garvieae DCC43. Gabrielsen C, Brede DA, Hernández PE, Nes IF, Diep DB. J Bacteriol. 2012 Dec; 194(24):6976-7. doi: 10.1128/JB.01864-12.

Novel Podoviridae family bacteriophage infecting Weissella cibaria isolated from Kimchi. Kleppen HP, Holo H, Jeon SR, Nes IF, Yoon SS. Appl Environ Microbiol. 2012 Oct; 78(20):7299-308. doi: 10.1128/AEM.00031-12. Epub 2012 Aug 10.

Construction and application of a luxABCDE reporter system for real-time monitoring of Enterococcus faecalis gene expression and growth. La Rosa SL, Diep DB, Nes IF, Brede DA. Appl Environ Microbiol. 2012 Oct; 78(19):7003-11. doi: 10.1128/AEM.02018-12. Epub 2012 Jul 27.

Characterization of a Leuconostoc bacteriophage infecting flavor producers of cheese starter cultures. Kleppen HP, Nes IF, Holo H. Appl Environ Microbiol. 2012 Sep; 78(18):6769-72. doi: 10.1128/AEM.00562-12. Epub 2012 Jul 13.

Paratransgenesis: an approach to improve colony health and molecular insight in honey bees (Apis mellifera)? Rangberg A, Diep DB, Rudi K, Amdam GV. Integr Comp Biol. 2012 Jul; 52(1):89-99. doi: 10.1093/icb/ics089. Epub 2012 Jun 1.

Natural antimicrobial peptides from bacteria: characteristics and potential applications to fight against antibiotic resistance. Hassan M, Kjos M, Nes IF, Diep DB, Lotfipour F. J Appl Microbiol. 2012 Oct; 113(4):723-36. doi: 10.1111/j.1365-2672.2012.05338.x. Epub 2012 Jun 8.

Prevalence of bacteriocin activities and bacteriocin-encoding genes in enterococcal clinical isolates in Iran. Hassan M, Diep DB, Javadzadeh Y, Dastmalchi S, Nes IF, Sharifi Y, Yari S, Farajnia S, Lotfipour F. Can J Microbiol. 2012 Apr; 58(4):359-68. doi: 10.1139/w11-136. Epub 2012 Mar 13.

The maltose ABC transporter in Lactococcus lactis facilitates high-level sensitivity to the circular bacteriocin garvicin ML. Gabrielsen C, Brede DA, Hernández PE, Nes IF, Diep DB. Antimicrob Agents Chemother. 2012 Jun; 56(6):2908-15. doi: 10.1128/AAC.00314-12. Epub 2012 Mar 12.

Growth rate-dependent control in Enterococcus faecalis: effects on the transcriptome and proteome, and strong regulation of lactate dehydrogenase. Mehmeti I, Faergestad EM, Bekker M, Snipen L, Nes IF, Holo H. Appl Environ Microbiol. 2012 Jan; 78(1):170-6. doi: 10.1128/AEM.06604-11. Epub 2011 Oct 28.


Target recognition, resistance, immunity and genome mining of class II bacteriocins from Gram-positive bacteria. Kjos M, Borrero J, Opsata M, Birri DJ, Holo H, Cintas LM, Snipen L, Hernández PE, Nes IF, Diep DB. Microbiology. 2011 Dec; 157(Pt 12):3256-3267. doi: 10.1099/mic.0.052571-0. Epub 2011 Oct 6.

Mechanisms of resistance to bacteriocins targeting the mannose phosphotransferase system. Kjos M, Nes IF, Diep DB. Appl Environ Microbiol. 2011 May; 77(10):3335-42. doi: 10.1128/AEM.02602-10. Epub 2011 Mar 18.

Transcriptome, proteome, and metabolite analyses of a lactate dehydrogenase-negative mutant of Enterococcus faecalis V583. Mehmeti I, Jönsson M, Fergestad EM, Mathiesen G, Nes IF, Holo H. Appl Environ Microbiol. 2011 Apr; 77(7):2406-13. doi: 10.1128/AEM.02485-10. Epub 2011 Feb 4.

Wide-inhibitory spectra bacteriocins produced by Lactobacillus gasseri K7. Zorič PM, Čanžek MA, Holo H, Nes IF, Salehian Z, Berlec A, Rogelj I. Probiotics Antimicrob Proteins. 2010 Dec; 2(4):233-40. doi: 10.1007/s12602-010-9044-5.

Characterization of garvicin ML, a novel circular bacteriocin produced by Lactococcus garvieae DCC43, isolated from mallard ducks (Anas platyrhynchos). Borrero J, Brede DA, Skaugen M, Diep DB, Herranz C, Nes IF, Cintas LM, Hernández PE. Appl Environ Microbiol. 2011 Jan; 77(1):369-73. doi: 10.1128/AEM.01173-10. Epub 2010 Nov 5.

The unconventional antimicrobial peptides of the classical propionibacteria. Faye T, Holo H, Langsrud T, Nes IF, Brede DA. Appl Microbiol Biotechnol. 2011 Feb; 89(3):549-54. doi: 10.1007/s00253-010-2967-7. Epub 2010 Oct 31.


An extracellular loop of the mannose phosphotransferase system component IIC is responsible for specific targeting by class IIa bacteriocins. Kjos M, Salehian Z, Nes IF, Diep DB. J Bacteriol. 2010 Nov; 192(22):5906-13. doi: 10.1128/JB.00777-10. Epub 2010 Sep 24.

Specific degradation of the mucus adhesion-promoting protein (MapA) of Lactobacillus reuteri to an antimicrobial peptide. Bøhle LA, Brede DA, Diep DB, Holo H, Nes IF. Appl Environ Microbiol. 2010 Nov; 76(21):7306-9. doi: 10.1128/AEM.01423-10. Epub 2010 Sep 10.

Class IIa bacteriocin resistance in Enterococcus faecalis V583: the mannose PTS operon mediates global transcriptional responses. Opsata M, Nes IF, Holo H. BMC Microbiol. 2010 Aug 25; 10:224. doi: 10.1186/1471-2180-10-224.

Nukacin 3299, a lantibiotic produced by Staphylococcus simulans 3299 identical to nukacin ISK-1. Ceotto H, Holo H, da Costa KF, Nascimento Jdos S, Salehian Z, Nes IF, Bastos Mdo C. Vet Microbiol. 2010 Nov 20; 146(1-2):124-31. doi: 10.1016/j.vetmic.2010.04.032. Epub 2010 May 11.

Use of the yeast Pichia pastoris as an expression host for secretion of enterocin L50, a leaderless two-peptide (L50A and L50B) bacteriocin from Enterococcus faecium L50. Basanta A, Gómez-Sala B, Sánchez J, Diep DB, Herranz C, Hernández PE, Cintas LM. Appl Environ Microbiol. 2010 May; 76(10):3314-24. doi: 10.1128/AEM.02206-09. Epub 2010 Mar 26.

The abi proteins and their involvement in bacteriocin self-immunity. Kjos M, Snipen L, Salehian Z, Nes IF, Diep DB. J Bacteriol. 2010 Apr; 192(8):2068-76. doi: 10.1128/JB.01553-09. Epub 2010 Feb 12.

Molecular and genetic characterization of a novel bacteriocin locus in Enterococcus avium isolates from infants. Birri DJ, Brede DA, Forberg T, Holo H, Nes IF. Appl Environ Microbiol. 2010 Jan; 76(2):483-92. doi: 10.1128/AEM.01597-09. Epub 2009 Nov 20

Published 11. February 2020 - 15:14 - Updated 29. May 2020 - 9:23