A substantial amount of scientific documentation is mounting for the significance of the gastrointestinal microbiota (gut or GI microbiota) on human health. In addition to the obvious connection between the gut microbiota and inflammation in the colon (leading to IBD, IBS and possibly colon cancer), recent articles have highlighted the not-so-obvious connection between the gut microbiota and the brain and cardiovascular system.
Despite several major breakthrough discoveries of the importance of the gut microbiota in human health, this information has not yet been transformed into diagnostic or therapeutic approaches. A major bottleneck in the gut microbiota diagnostics is the reproducibility and throughput of the analytical approaches used.
We pressent a review of the current status for the use of gut bacteria in disease diagnostics: