The aim of this work was to use the information from genome sequence databases to address the correlation between rRNA gene phylogeny and total gene composition in bacteria. We found that Actinobacteria were positively associated with kinases, while Gamma-proteobacteria were positively associated with methylases and acyltransferases. The suggested functional differences between higher phylogroups, however, need experimental verification.
For more details see: High or low correlation between co-occuring gene clusters and 16S rRNA phylogeny. Rudi K, Sekelja M. FEMS Microbiol Lett. 2012 Nov 9. doi: 10.1111/1574-6968.12042. [Epub ahead of print]