Course code MINA410

MINA410 Environmental Radiobiology

There may be changes to the course due to to corona restrictions. See Canvas and StudentWeb for info.

Norsk emneinformasjon

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Showing course contents for the educational year 2021 - 2022 .

Course responsible: Deborah Helen Oughton
Teachers: Justin Emrys Brown, Carmel Mothersill, Colin Brian Seymour
ECTS credits: 5
Faculty: Faculty of Environmental Sciences and Natural Resource Management
Teaching language: EN
(NO=norsk, EN=Engelsk)
Limits of class size:
Minimum 6; maximum 25 students
Teaching exam periods:
This course starts in June block. This course has teaching/evaluation in August block, June block.
Course frequency: Odd years, next schedule June 2021.
First time: 2010H
Preferential right:
-
Course contents:
The course is based on a weeks intensive lectures. Students are expected to have read and prepared from the pensum beforehand. One afternoon will include lab demonstration of some of the biomarker methods. An additional indepth self-study on a selected topic will be required for the written assignment. The course is held every other year.
Learning outcome:
The aim of the course is to give students an introduction to the fundamental principles of radiobiology, within the context of research fields on radioecology and the environmental effects of radiation. As such the course will cover both the history and the state-of-the-art of our knowledge on the biological effects of radiation on humans, and how this relates to other effects seen in non-human organisms. Areas covered include fundamental radiobiology, biological responses to ionising radiation, the use of biomarkers and toxicogenomics, factors linked to differences in radiation sensitivity, non-targeted effects (bystander, genomic instability, adaptive response, etc.,) and multiple stressors.
Learning activities:
The various concepts of radiobiology (such as target theory) will be introduced as problems for the class to discuss. Following the class discussion and the production of a hypothesis, the classical solutions and work in this area will be discussed. Repetition of this approach will allow students to become immersed in the topic, and will encourage them to derive the fundamental tenets of radiobiology for themselves. Lectures will be supported by two half days of practical work demonstrating how classic radiation effect biomarkers (chromosome aberration, bystander effects, etc) can be applied in radioecology. 
Teaching support:
Students will have access to all guest lecturers during joint lunches for the duration of the course. Each student will be assigned a mentor for the course assignment.  
Syllabus:

Course book:

Eric Hall 'Radiobiology for the Radiologist'

 

Selected articles (available as a compendium)from:

Essentials of Environmental Toxicology, by W Hughes, publ Taylor and Francis

 

In vitro methods in aquatic toxicology Mothersill and Austin -#8211- publ Praxis Fundamentals of Aquatic Toxicology Rand, publ Taylor and Francis

 

Multiple stressors a challenge for the future, Proc. NATO ARW eds Mothersill, Mosse and Seymour Publ Springer

Prerequisites:
Basic principles of radiation protection (eg. KJM350 or similar)
Recommended prerequisites:
Mandatory activity:
Lectures and practicals (80% attendance) Written assignment
Assessment:

The students will prepare a written assignment on a choice of topics.

Grading scale: Passed / Not passed

Nominal workload:

The course is based on one week of intensive lectures and practicals. Students are expected to have read and prepared from the pensum beforehand. One afternoon will include lab demonstration of some of the biomarker methods. An additional in-depth self-study on a selected topic will be required for the written assignment.

Total hours: 125

Entrance requirements:
Minimum requirements for entrance to higher education in Norway (generell studiekompetanse)
Reduction of credits:
-
Type of course:
30 hrs lectures/practicals, 20 hrs preparation/self-study, 75 hrs written assignment
Note:
The next course is planned for June 2021, however this is on the condition that  face-to-face teaching is permitted, and lecturers are permitted to travel.  This course is not suitable for online teaching. 
Examiner:
External examiner will control the quality of the assigments
Examination details: Term paper: Passed / Failed