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Irma Caroline Oskam

Irma Caroline Oskam

Underdirektør

  • Senter for husdyrforsøk

Wide experienced, positive and collective leader with a strong academic record and interest in strategic management. I am motivated by professional interest and ambition to deliver the maximum. As a researcher with broad- and long experience in the field of veterinary- and agriculture sciences and biotechnology, I am profoundly interested in the creation of sustainable values within agriculture and the support of global human health dependent on plants and animals. 

Besides being the leader of NMBUs livestock research farm, I am still active as a researcher. As qualified professor in the field of reproductive biology and biotechnology and with a wide national- and international network within educational- and research institutions I am aware of my current fortunate position: department director of Norway’s largest educational- and research facilities within production animals and agriculture, thus bringing science and innovation closer to society, policymakers and industrial stakeholders.

The Livestock Production Research Centre is part of the Norwegian University of Life Sciences where research, education and innovation provide best animal Health and Welfare in close contact with human environment. As a researcher I am currently involved in the following projects: Smartfarming (infrastructure), Holoruminants (H2020), 3D Omics (H2020), Optimization of Embryo Production in Norwegian cattle breeds (NFR).

  • Liste med publikasjoner fra min forskning. (Cristin)

    Thesis for the Degree of PhD: Effects of Organochlorine Contaminants on Mammalian Reproductive and Endocrine Systems. Studies on functional changes in steroid hormones and reproductive parameters in mice, goats and polar bears. 2004. ISBN82-7725-100-9

     

    1. Oskam, I.C.; Ropstad, E.; Lie, E.; Derocher, A.; Wiig, Ø.; Dahl, E.; Larsen, S.; Wiger, R. and Skaare, J.U. 2003. Organochlorines Affect the Major Androgenic Hormone, Testosterone, in Male Polar Bears (Ursus maritimus) At Svalbard. J. Toxicol. Environ. Health A: 66:2119-2139.

     

    1. Lyche, J.L.; Oskam, I.C.; Skaare, J.U.; Farstad, W.; Reksen, O.; Sweeney T.; E Dahl, E.; and Ropstad, E. 2003. Effects of Gestational and Lactational Exposure to Low Doses of PCBs 126 and 153 on Anterior Pituitary and gonadal hormones and on Puberty in Female Goats. Reprod. Toxicol. 19, 87-95.

               

    1. Lyche, J.L.; Oskam, I.C.; Krogenes, A.; Skaare, J.U.; Reksen, O.; Sweeney, T.; Dahl, E.; and Ropstad, E. 2003. Perinatal exposure to polychorinated biphenyl 153 affect endocrine function and puberty maturation in goats. Reprod.Domestic. Anim. 38 (4):264.

     

    1. Oskam, I.C.; Ropstad, E.; Lie, E.; Derocher, A.; Wiig, Ø.; Dahl, E.; Larsen, S. and Skaare, J.U. 2004. Organochlorines affect the steroid hormone cortisol in polar bears (Ursus maritimus) at Svalbard, Norway. J. Toxicol. Environ. Health A: 67:959-977.

     

    1. Oskam, I.C.; Ropstad, E.; Smith, A.J; Dahl, E., Skaare, J.U.; Tverdal, A.; Andersen Berg, K. and Wiger, R. 2004. Effects of PCB99 and PCB153 exposure on spermatogenesis in young adult C57BL6 mice. Reprod. Toxicol. 19(2), 169-80.       

     

    1. Oskam, I.C.; Lyche, J.L.; Krogenaes, A.; Thomassen, R.; Skaare, J.U.; Wiger, R.; Dahl, E.; Sweeney T, Stien, A.; and Ropstad, E. 2005. Effects of long-term maternal exposure to low doses of PCB126 and PCB153 on the endocrine and male reproductive systems of young male goats. Reproduction 130, 1-13.

     

    1. Ropstad, E.; Oskam, I.C.; Lyche J.L.; Lie, E.; Braathens, M.; Larsen, H.J.; Dahl, E.; Wiger, R. and Skaare, J.U. 2005. Endocrine disruption caused by organochlorines (OC’s). Field studies and experimental models.  J. Toxicol. Environ. Health A: 69.

     

    1. Oskam, I.C.; Ropstad, E.; and Andresen, Ø. Project no. 164070/I10. Testicular activity in boars related to the occurrence of androstenone in fat. 2006. Report: Evaluation of the National Norwegian Research programme on male pigs.

     

    1. Oskam, I.C.; Ropstad, E.; Andersen Berg, K.; Dahl, E.; Larsen, S.; Fredriksen, B. and Andresen, Ø. 2007. Testicular germ cell development in relation to 5α-androstenone levels in pubertal entire male pigs. Theriogenology. 69 (8): 967-976.

     

    1. Zamaratskaia, G.; Oskam, I.C.; Ropstad, E.; Tajet, H.; Dahl, E, and Andresen Ø. 2008. Effects of hCG stimulation on hepatic activities of cytochrome P4502E1 and P4502A in pubertal male pigs. Reprod. Domestic Animals.43 147-152.

     

    1. Krogenaes, A.; Taubøll, E.; Stien, A.; Oskam, I.C.; Lyche, J.L.; Dahl, E., Thomassen R.; and Ropstad, E. 2008. Valproat (VPA) affects reproductive endocrine function, testis diameter and some semen parameter in non-epileptic adolescent male goats. Theriogenology, 1; 70 (1): 15-26.

     

    1. Irma C. Oskam & Annete Haugen. Tilbyr nedfrysing av eggstokkvev. 2009. Ønskebarn, Norsk forening for fertiltitet og barnløshet. nr. 3. 16-18.

     

    1. Oskam, I.C.; Lervik, S.; Tajet, H.; Dahl, E.; Ropstad, E. and Ø. Andresen. Differences in testosterone, androstenone and skatole levels in plasma and fat in response to hCG stimulation in pubertal purebred Duroc and Landrace boars. 2010. Theriogenology 74(6), 1088-98.

                                                 

    1. Oskam, I.C; Babak, A.; Santos, R.R. Histologic and ultra-structural features of cryopreserved ovine ovarian tissue: deleterious effect of 1,2-propanediol applying different thawing protocols. 2010. Fertility & Sterility: 93(8): 2764-2766.

     

    1. Melo, M.A.P.; Oskam I.C.;  Celestino, J.J.H.; Figueiredo, J.R.; Rodrigues, A.P.R.; Santos, R.R. Adding Ascorbic Acid to vitrification and IVC medium influences follicle morphology, but not viability 2010. J Reprod. Animals 2010: DOI: 101111/j. 1439-0531.2010.01716.

     

    1. Zimmer, K.E.; Gutleb; A.C., Lyche; J.L., Dahl, E.; Oskam I.C.; Krogenæs, A.; Skaare, J.U.; Ropstad, E. Altered stress-induced cortisol levels in goats exposed to Polychlorinated Biphenyls (PCB 126 and PCB 153) during fetal and post-natal development. 2010. J Toxicol Environ Health A.: 72(3-4): 164-172.

     

    1. Oskam I.C.; Lund T.; Santos R.R. Irreversible damage in ovine ovarian tissue after cryopreservation in propanediol: analyses after in vitro culture and xenotransplantation. J Reprod. Animals. 2011: 46(5):793-9.
    1. Stensvold, E.; Magelssen, H.; Oskam, I.C. Fertilitetsbevarende tiltak hos gutter og unge menn med kreft. Oversiktsartikkel. 2011, Tidskrift for den norske legeforening. 15/2011. 9:131 (15):1433-5.

     

    1. Stensvold, E.; Magelssen, H.; Oskam I.C. Fertilitetsbevarende tiltak hos jenter og unge kvinner med kreft. Oversiktsartikkel. 2011, Tidskrift for den norske legeforening. 15/2011. 9:131 (15):1429-32.

     

    1. Almeida, D.V. Haritova, A.M., Oskam, I.C., Santos, R.R. Scalercio, S.R., Domingues. Morphological and morphometrical characterization, and estimation of population of preantral ovarian follicles from senile common squirrel monkey (Saimiri sciureus). 2012. Anim Reprod Sci. 134(3-4):210-5

       

    1. Figenschou, L; Folstad, I; Rudolfsen, G; Hanssen, S.A; Kortet, R; Skau, P.A; Killie, J.E; Oskam, I.C; Strand, H. The relative effect of parasites and social status on sperm traits in Arctic charr (Salvelinus alpinus). 2012. Behavioral Ecology. doi:10.1093

     

    1. Santana, L.N.; Brito, A.B.; Brito, D.C.; Oskam I.C.; Van den Hurk, R.; Domingues, S.F.S.; Santos, R.R. Vitrification of ovarian tissue from human and large mammals: an overview. 2012. Biopreservation and Biobanking. 10(3):288-94.

     

    1. Lervik, S.; Oskam, I.C.; Krogenæs, A.; Tajet, H.; Haga, A.; Andresen, Ø.; Dahl, E.; Olsaker, I.; Ropstad, E. A longitudinal study on androstenone and testosterone levels and testicular morphology of Duroc boars with estimated breeding value for androstenone. 2013. 1;79(6):986-94.

     

    1. Jahnukainen K, Tinkanen H, Wikström A, Dunkel L, Saarinen-Pihkala U, Mäkinen S, Asadi B, Oskam I.C, Vettenranta K, Laine T, Kairisto V, Juvonen V. Bone marrow remission status predicts leukemia contamination in ovarian biopsies collected for fertility preservation. 2013. Leukemia. 2013. 27(5):1183-5.

     

    1. Brito, A.B.; Brito, D.C.; Oskam I.C.; Rocha, R.M. Van den Hurk, R.; Domingues, S.F.S.; Paris M.C.J.; Santos, R.R. Vitmain E-analog Torlox prevents endoplasmic reticulum stress in fozen-thawed ovarian tissue of capuchin monkey (Sapajus appella) ovarian tissue. 2014. Cell Tissue Res. 355(2): 471-80.

     

    1. Lervik S, Kristoffersen A, Olsaker I, Oskam I.C, Anette Krogenæs A, Nagstrup Conley L, Hedegaard J, Ropstad E. Gene expression during testis development in Duroc boars. A longitudinal microarray study. 9(11):1832-422015. 2015.

     

    1. B Asadi A., M Sheikhi, IC Oskam, M Nurmio, T Laine, H Tinkanen, S Mäkinen, TG Tanbo, O Hovatta, K Jahnukainen. Effects of previous chemotherapy on the quality of cryopreserved human ovarian tissue in vitro. PLoS One. 2015. 30;10(7).

     

    1. In vivo effects of imatinib, tyrosine kinase inhibitor on postnatal rat’s ovary. B Asadi A., R.R. Santos, M Nurmio, M van Duursen, B Roelen, K Jahnukainen, IC Oskam. 2014.

     

    1. Trolox enhances follicular survival after ovarian tissue autograft in squirrel monkey (Saimiri collinsi). R.R.A. Scalercio, C.A. Amorim, D.C. Brito, S. Percário, I. C. Oskam, S.F.S. Domingues, R.R. Santos. Reprod Fertil Dev. 2015 May 21. doi: 10.1071/RD14454.

     30.  Risk assessment of dietary cadmium exposure in the Norwegian population. Opinion of the Panel on Contaminants of the Norwegian Scientific Committee for Food Safety

     

    Knutsen, Helle Katrine; Amlund, Heidi; Brantsæter, Anne Lise; Engeset, Dagrun; Fæste, Christiane Kruse; Holene, Edel; Ruus, Anders; Lillegaard, Inger Therese L.; Eriksen, Gunnar Sundstøl; Kvalem, Helen Engelstad; Miles, Christopher Owen; Nordeng, Hedvig Marie Egeland; Oskam, Irma Caroline; Thomsen, Cathrine; Skåre, Janneche Utne(VKM Report, Research report, 2015)

     

    31.  Risk assessment of dietary exposure to acrylamide in the Norwegian population. Opinion of the Panel on Contaminants of the Norwegian Scientific Committee for Food Safety

    Brantsæter, Anne Lise; Knutsen, Helle Katrine; Lillegaard, Inger Therese L.; Amlund, Heidi; Eriksen, Gunnar Sundstøl; Fæste, Christiane Kruse; Kvalem, Helen Engelstad; Miles, Christopher Owen; Oskam, Irma Caroline; Ruus, Anders; Thomsen, Cathrine; Skåre, Janneche Utne(VKM Report, Research report, 2015)

     

    1. B Asadi A., M Sheikhi, K Jahnukainen M Nurmio, T Laine, H Tinkanen, S Mäkinen, O Hovatta, IC Oskam. K. Jahnukainen. Minimal residual disease of leukemia and the the quality of cryopreserved human ovarian tissue in vitro. Leuk Lymfoma 57:3.700-7.

     

    1. Asadi-Azarbaijani, RR. Santos, K. Jahnukainen, S. Braber, M.B.M. van Duursen, Jorma Toppari, O.D. Saugstad, M. Nurmio, and IC. Oskam. Developmental effects of imatinib mesylate on rat folliculogenesis. 2017. Reprod Biol 17:1 25-33.

     

    1. Oskam I.C. Embryologi som del av avlsarbeidet. Buskap 4-2016.

     

    1. The quality of cryopreserved ovarian tissue used for fertility preservation in pediatric and young adult cancer Babak Asadi-Azarbaijani. Main supervisor. 2017. Norwegian National Advisory Unit on Women’s Health, Women’s Division, OUS.

     Babak Asadi-Azarbaijania, Saskia Braber, Majorie van Duursen, Kirsi Jahnukainen,

    Regiane Santos, Irma Oskam. Imatinib mesylate does not counteract ovarian tissue fibrosis in postnatal rat ovary. Reprod. Biol. 2019. https://doi.org/10.1016/j.repbio.2019.03.003

     

    1. Valentina Pampanini, Magdalena Wagner, Babak Asadi Azarbaijani, Irma C. Oskam, Mona Sheikhi, Marcus O.D. Sjödin, Johan Lindberg, Outi Hovatta, Lena Sahlin, Richelle Duque Björvang‎, Marjut Otala, Pauliina Damdimopoulou, Kirsi Jahnukainen. Impact of first-line cancer treatment on the follicle quality in ovarian cortex samples cryopreserved for fertility preservation from pediatric and adolescent patients. Human Reproduction. 2019 Aug 14. pii: dez125. doi: 10.1093/humrep/dez125.

     

    1. Danuza Leite Leão, Sheyla Farhayldes Souza Domingues, Patrícia da Cunha Sousa, Wlaisa Vasconcelos Sampaio, Fábio Roger Vasconcelos, Arlindo Alencar Moura, Regiane Rodrigues dos Santos, Morten Skaugen, Irma Caroline Oskam. Seminal quality and global proteomic analysis of spermatozoa from captive Amazon squirrel 2 monkeys (Saimiri collinsi Osgood, 1916) during the dry and rainy seasons. September 2019. https://doi.org/10.1101/771295

     

    1. Danuza L Leão, Wlaisa V Sampaio , Patrícia C Sousa , Arlindo A A Moura , Irma C Oskam , Regiane R Santos  , Sheyla F S Domingues .  Micromorphological and ultrastructural description of spermatozoa from squirrel monkeys ( Saimiri collinsi Osgood, 1916). 2020. Zygote Jun;28(3):203-207. doi: 10.1017/S0967199419000868

     

    1. Reina Jochems, Ann Helen Gaustad, Louisa J. Zad, Eli Grindfla, Irma C. Oskae, Teklu T. Zeremichac, Frøydis D. Myromslien, Elisabeth Kommisrud, Anette K. Krogenæs.. Ovarian characteristics, and in vitro nuclear and cytoplasmic oocyte maturation in Duroc and Landrace pigs. Vet Med Sci. 2021 May 3.doi: 10.1002/vms3.498. 

     

     

    1. Danuza L Leão, Wlaisa V Sampaio , Patrícia C Sousa , Arlindo A A Moura , Irma C Oskam , Regiane R Santos  , Sheyla F S Domingues .The use of anogenital distance as a noninvasive predictor of seminal quality in captive squirrel monkey ( Saimiri collinsi Osgood 1961). Journal of Medical Primatology 21-602-R1.

     

    1. Mirja Nurmio, Babak Asadi-Azarbaijani, Mi Hou, Ronja Kiviö, Jorma Toppari, Helena Tinkanen, Tiina Laine, Irma C. Oskam and Kirsi Jahnukainen Effect of Previous Alkylating Agent Exposure on Follicle Numbers in Cryopreserved Prepubertal and Young Adult Ovarian Tissue after Long-Term Xenografting. 2022. 10.3390/cancers14020399.
    2. Reina Jochems, Ann Helen Gaustad, Louisa J. Zak, Irma C. Oskam, Teklu T. Zeremichael, Eli Grindflek, Frøydis D. Myromslien, Elisabeth Kommisrud, Anette K. Krogenæs. Effect of two ‘progressively motile sperm-oocyte’ ratios on porcine in vitro fertilization and embryo development. April 2022. DOI:10.1017/S0967199422000053

     

    1. Reina Jochems, Ann Helen Gaustad, Bjarne Styrishave, Louisa J. Zak, Irma C. Oskam, Teklu T. Zeremichael, Eli Grindflek, Frøydis D. Myromslien, Elisabeth Kommisrud, Anette K. Krogenæs.

    Follicular fluid steroid analysis and in vitro embryo development in Duroc and Landrace pigs. Submitted Theriogenology. March 2022,