Publications

Preprints

Heidi Kristine Grønlien, Romain Fontaine, Kjetil Hodne, Isabelle Tysseng, Eirill Ager-Wick, Finn-Arne Weltzien & Trude Marie Haug. Gonadotropes in medaka grow long extensions with varicosity-like swellings, projecting towards each other and blood vessels. BioRxiv 21 September 2019. doi: 10.1101/777151

2020

Romain Fontaine, Eirill Ager-Wick, Kjetil Hodne & Finn-Arne Weltzien. Plasticity in medaka gonadotropes via cell proliferation and phenotypic conversion. J. Endocrinol. 245, 21-37. doi: 10.1530/JOE-19-0405

Romain Fontaine, Elia Ciani, Trude M. Haug, Kjetil Hodne, Eirill Ager-Wick, Dianne M. Baker & Finn-Arne Weltzien. Gonadotrope plasticity at cellular, population and structural levels: A comparison between fishes and mammals. Gen. Comp. Endocrinol. 287, 113344. doi: 10.1016/j.ygcen.2019.113344

2019

Kjetil Hodne, Romain Fontaine, Eirill Ager-Wick & Finn-Arne Weltzien. Gnrh1-induced responses are indirect in female medaka Fsh cells, generated through cellular networks. Endocrinology 160, 3018-3032. doi: 10.1210/en.2019-00595

Elia Ciani, Romain Fontaine, Gersende Maugars, Rasoul Nourizadeh-Lillabadi, Eva Andersson, Jan Bogerd, Kristine von Krogh & Finn-Arne Weltzien. Gnrh receptor gnrhr2bbα is expressed exclusively in lhb-expressing cells in Atlantic salmon male parr. Gen. Comp. Endocrinol. 285, 113293. doi: 10.1016/j.ygcen.2019.113293

Kristine von Krogh, Erik Ropstad, Rasoul Nourizadeh-Lillabadi, Trude Marie Haug & Finn-Arne Weltzien. In vitro effects of bisphenol A and tetrabromobisphenol A on cell viability and reproduction-related gene expression in pituitaries from sexually maturing Atlantic cod (Gadus morhua L.). Fishes 4, 48. doi: 10.3390/fishes4030048

Susann Burow, Naama Mizrahi, Gersende Maugars, Kristine von Krogh, Rasoul Nourizadeh-Lillabadi, Lian Hollander-Cohen, Michal Shpilman, Ishwar Atreb, Finn-Arne Weltzien & Berta Levavi-Sivan. Characterization of gonadotropin receptors Fshr and Lhr in Japanese medaka, Oryzias latipes. Gen. Comp. Endocrinol. 285, 113276. doi: 10.1016/j.ygcen.2019.113276

Geir Halnes, Simen Tennøe, Trude M. Haug, Gaute T. Einevoll, Finn-Arne Weltzien & Kjetil Hodne. A computational model for gonadotropin releasing cells in the teleost fish medaka. PLoS Comput. Biol. 15, e1006662. doi:10.1371/journal.pcbi.1006662

Kristine von Krogh, Gunnveig Toft Bjørndal, Rasoul Nourizadeh-Lillabadi, Erik Ropstad, Trude M. Haug & Finn-Arne Weltzien. Cortisol differentially affects cell viability and reproduction-related gene expression in Atlantic cod pituitary cultures dependent on stage of sexual maturation. Comp. Biochem. Physiol. A Mol. Integr. Physiol. 236, 110517. doi: 10.1016/j.cbpa.2019.06.017

Elia Ciani, Romain Fontaine, Gersende Maugars, Naama Mizrahi, Ian Mayer, Berta Levavi‐Sivan & Finn‐Arne Weltzien. Melatonin receptors in Atlantic salmon stimulate cAMP levels in heterologous cell lines and show season‐dependent daily variations in pituitary expression levels. J. Pineal. Res. e12590. doi: 10.1111/jpi.12590

Romain Fontaine & Finn-Arne Weltzien. Labeling of blood vessels in the teleost brain and pituitary using cardiac perfusion with a DiI-fixative. J. Vis. Exp. 148, e59768. doi: 10.3791/59768

Simen Tennøe, Kjetil Hodne, Trude M. Haug, Finn-Arne Weltzien, Gaute T. Einevoll & Geir Halnes. [Re] Fast-activating voltage- and calcium-dependent potassium (BK) conductance promotes bursting in pituitary cells: a dynamic clamp study. ReScience 5(1), 2. doi: 10.5281/zenodo.2611252, (direct link to PDF)

Mitchell S. Fleming, Gersende Maugars, Anne-Gaëlle Lafont, Jocelyn Rancon, Romain Fontaine, Rasoul Nourizadeh-Lillabadi, Finn-Arne Weltzien, Elena Santidrian Yebra-Pimentel, Ron Dirks, Stephen D. McCormick, Karine Rousseau, Patrick Martin & Sylvie Dufour. Functional divergence of thyrotropin beta-subunit paralogs gives new insights into salmon smoltification metamorphosis. Sci. Rep. 9, 4561. doi: 10.1038/s41598-019-40019-5

Romain Fontaine, Eirill Ager-Wick, Kjetil Hodne & Finn-Arne Weltzien. Plasticity of Lh cells caused by cell proliferation and recruitment of existing cells. J. Endocrinol. 240, 361-377. doi: 10.1530/JOE-18-0412

Susann Burow, Romain Fontaine, Kristine von Krogh, Ian Mayer, Rasoul Nourizadeh-Lillabadi, Lian Hollander-Cohen, Yaron Cohen, Michal Shpilman, Berta Levavi-Sivan, & Finn-Arne Weltzien. Data on Western blot and ELISA analysis of medaka (Oryzias latipes) follicle-stimulating hormone (Fsh) and luteinizing hormone (Lh) using recombinant proteins expressed with Pichia pastoris. Data Brief. 22, 1057-1063. doi: 10.1016/j.dib.2019.01.034

Susann Burow, Romain Fontaine, Kristine von Krogh, Ian Mayer, Rasoul Nourizadeh-Lillabadi, Lian Hollander-Cohen, Yaron Cohen, Michal Shpilman, Berta Levavi-Sivan, & Finn-Arne Weltzien. Medaka follicle-stimulating hormone (Fsh) and luteinizing hormone (Lh): Developmental profiles of pituitary protein and gene expression levels. Gen. Comp. Endocrinol. 272, 93-108. doi: 10.1016/j.ygcen.2018.12.006

 

2018

Ager-Wick, Eirill; Hodne, Kjetil; Fontaine, Romain; von Krogh, Kristine; Haug, Trude; Weltzien, Finn-Arne.

Preparation of a High-quality Primary Cell Culture from Fish Pituitaries. Journal of Visualized Experiments 2018 

 

Fontaine, Romain; Hodne, Kjetil; Weltzien, Finn-Arne.

Healthy Brain-pituitary Slices for Electrophysiological Investigations of Pituitary Cells in Teleost Fish. Journal of Visualized Experiments 2018

 

2017

Candelma, Michela; Fontaine, Romain; Colella, Sabrina; Santojanni, Alberto; Weltzien, Finn-Arne; Carnevali, Oliana.

Gonadotropin characterization, localization and expression in the European hake (Merluccius merluccius). Reproduction 2017 ;Volum 153.(2) s. 123-132

 

Jansen, Hans J.; Liem, Michael; Jong-Raadsen, Susanne A.; Dufour, Sylvie; Weltzien, Finn-Arne; Swinkels, William; Koelewijn, Alex; Palstra, Arjan P.; Pelster, Bernd; Spaink, Herman P.; van den Thillart, Guido E.; Dirks, Ron P.; Henkel, Christiaan V.

Rapid de novo assembly of the European eel genome from nanopore sequencing reads. Scientific Reports 2017 ;Volum 7.(1)

 

Morini, Marina; Penaranda, David S.; Vílchez, María C.; Nourizadeh-Lillabadi, Rasoul; Lafont, Anne-Gaëlle; Dufour, Sylvie; Asturiano, Juan F.; Weltzien, Finn-Arne; Pérez, Luz.

Nuclear and membrane progestin receptors in the European eel: Characterization and expression in vivo through spermatogenesis. Comparative Biochemistry and Physiology A 2017 ;Volum 207. s. 79-9

 

von Krogh, Kristine; Bjørndal, Gunnveig Toft; Nourizadeh-Lillabadi, Rasoul; Hodne, Kjetil; Ropstad, Erik; Haug, Trude M; Weltzien, Finn-Arne.

Sex steroids differentially regulate fshb, lhb and gnrhr expression in Atlantic cod (Gadus morhua). Reproduction 2017 ;Volum 154.(5) s. 581-594

 

2016

Griffiths, Gareth Wyn; Müller, Ference; Ledin, Johan; Patton, E. Elizabeth; Gjøen, Tor; Lobert, Viola; Winther-Larsen, Hanne Cecilie; Mullins, Mary; Joly, Jean-Stephane; Weltzien, Finn-Arne; Press, Charles McLean; Alestrøm, Peter.

Fish from Head to Tail: The 9th European Zebrafish Meeting in Oslo. Zebrafish 2016 ;Volum 13.(2) s. 132-137

 

Strandabø, Rønnaug; Grønlien, Heidi Kristine; Ager-Wick, Eirill; Nourizadeh-Lillabadi, Rasoul; Hildahl, Jon Paul; Weltzien, Finn-Arne; Haug, Trude M.

Identified lhb-expressing cells from medaka (Oryzias latipes) show similar Ca2+-response to all endogenous Gnrh forms, and reveal expression of a novel fourth Gnrh receptor. General and Comparative Endocrinology 2016 ;Volum 229. s. 19-31

 

Tysseng, Isabelle; Grønlien, Heidi Kristine; Weltzien, Finn-Arne; Haug, Trude.

Gnrh-induced Ca2+ responses in varicosity-like structures on membranous tubular extensions from Lh-producing gonadotropes in medaka (Oryzias latipes). 8th International Symposium on Fish Endocrinology; 2016-06-28 - 2016-07-02

 

2015

Hodne, Kjetil; Weltzien, Finn-Arne.

Single-cell isolation and gene analysis: Pitfalls and possibilities. International Journal of Molecular Sciences 2015 ;Volum 16.(11) s. 26832-26849

 

Morini, Marina; Penaranda, David Sanchez; Vílchez, María C.; Gallego, Victor; Nourizadeh-Lillabadi, Rasoul; Asturiano, Juan F.; Weltzien, Finn-Arne; Pérez, Luz.

Transcript levels of the soluble sperm factor protein phospholipase C zeta 1 (PLCζ1) increase through induced spermatogenesis in European eel. Comparative Biochemistry and Physiology A 2015 ;Volum 187. s. 168-176

 

2014

Ager-Wick, Eirill; Henkel, Christiaan V.; Haug, Trude M; Weltzien, Finn-Arne.

Using normalization to resolve RNA-seq biases caused by amplification from minimal input. Physiological Genomics 2014 ;Volum 46.(21) s. 808-820

 

Mazzeo, Ilaria; Penaranda, David Sanchez; Gallego, Victor; Baloche, S; Nourizadeh-Lillabadi, Rasoul; Tveiten, Helge; Dufour, S; Asturiano, Juan F; Weltzien, Finn-Arne; Perez, L.

Temperature modulates the progression of vitellogenesis in the European eel. Aquaculture 2014 ;Volum 434. s. 38-47

 

Penaranda, David Sanchez; Mazzeo, Ilaria; Gallego, Victor; Hildahl, Jon Paul; Nourizadeh-Lillabadi, Rasoul; Perez, L; Weltzien, Finn-Arne; Asturiano, Juan F.

The Regulation of Aromatase and Androgen Receptor Expression During Gonad Development in Male and Female European Eel. Reproduction in domestic animals (1990) 2014 ;Volum 59. s. 512-521

 

Sandvik, Guro Katrine; Hodne, Kjetil; Haug, Trude M; Okubo, Kataaki; Weltzien, Finn-Arne.

RFamide peptides in early vertebrate development. Frontiers in Endocrinology 2014 ;Volum 5:203.

 

Weltzien, Finn-Arne; Hildahl, Jon Paul; Hodne, Kjetil; Okubo, Kataaki; Haug, Trude M.

Embryonic development of gonadotrope cells and gonadotropic hormones - Lessons from model fish. Molecular and Cellular Endocrinology 2014 ;Volum 385.(1-2) s. 18-27

 

Weltzien, Finn-Arne; Hildahl, Jon Paul; Hodne, Kjetil; Okubo, Kataaki; Haug, Trude M.

Embryonic development of gonadotrope cells and gonadotropic hormones - Lessons from model fish. Molecular and Cellular Endocrinology 2014 ;Volum 385. s. 18-27

 

2013

Ager-Wick, Eirill; Dirks, Ron P.; Burgerhout, Erik; Nourizadeh-Lillabadi, Rasoul; de Wijze, Danielle L.; Spaink, Herman P.; van den Thillart, Guido; Tsukamoto, Katsumi; Dufour, Sylvie; Weltzien, Finn-Arne; Henkel, Christiaan V.

The pituitary gland of the European eel reveals massive expression of genes involved in the melanocortin system. PLoS ONE 2013 ;Volum 8.(10)

 

Hildahl, Jon Paul; Taranger, Geir Lasse; Norberg, Birgitta; Haug, Trude M; Weltzien, Finn-Arne.

Differential regulation of GnRH ligand and receptor genes in the brain and pituitary of Atlantic cod exposed to different photoperiod. General and Comparative Endocrinology 2013 ;Volum 180. s. 7-14

 

Hodne, Kjetil; Strandabø, Rønnaug; von Krogh, Kristine; Nourizadeh-Lillabadi, Rasoul; Sand, Olav; Weltzien, Finn-Arne; Haug, Trude M.

Electrophysiological differences between fshb- and lhb-expresing gonadotropes in primary culture. Endocrinology 2013 ;Volum 154.(9) s. 3319-3330

 

Hodne, Kjetil; Weltzien, Finn-Arne; Oka, Y; Okubo, K.

Expression and Putative Function of Kisspeptins and Their Receptors During Early Development in Medaka. Endocrinology 2013 ;Volum 154.(9) s. 3437-3446

 

Penaranda, David Sanchez; Mazzeo, I.; Hildahl, Jon Paul; Gallego, Victor; Nourizadeh-Lillabadi, Rasoul; Pérez, Luz; Asturiano, Juan F; Weltzien, Finn-Arne.

Molecular characterization of three GnRH receptor paralogs in the European eel, Anguilla anguilla: Tissue-distribution and changes in transcript abundance during artificially induced sexual development. Molecular and Cellular Endocrinology 2013 ;Volum 369.(1-2) s. 1-14

 

Strandabø, Rønnaug; Hodne, Kjetil; Ager-Wick, Eirill; Sand, Olav; Weltzien, Finn-Arne; Haug, Trude M.

Signal transduction involved in GnRH2-stimulation of identified LH-producing gonadotropes from lhb-GFP transgenic medaka (Oryzias latipes). Molecular and Cellular Endocrinology 2013 ;Volum 372.(1-2) s. 128-139

 

2012

Aroua, Salima; Maugars, Gersende; Jeng, Shan-Ru; Chang, Ching-Fong; Weltzien, Finn-Arne; Rousseau, Karine; Dufour, Sylvie.

Pituitary gonadotropins FSH and LH are oppositely regulated by the activin/follistatin system in a basal teleost, the eel. General and Comparative Endocrinology 2012 ;Volum 175.(1) s. 82-91

 

Henkel, Christiaan V.; Burgerhout, Erik; de Wijze, Danielle L.; Dirks, Ron P.; Minegishi, Yuki; Jansen, Hans J.; Spaink, Herman P.; Dufour, Sylvie; Weltzien, Finn-Arne; Tsukamoto, Katsumi; van den Thillart, Guido.

Primitive duplicate hox clusters in the European eel's genome. PLoS ONE 2012 ;Volum 7.(2)

 

Henkel, Christiaan V.; Dirks, Ron P.; de Wijze, Danielle L.; Minegishi, Yuki; Aoyama, Jun; Jansen, Hans J.; Turner, Ben; Knudsen, Bjarne; Bundgaard, Martin; Hvam, Kenneth Lyneborg; Boetzer, Marten; Pirovano, Walter; Weltzien, Finn-Arne; Dufour, Sylvie; Tsukamoto, Katsumi; Spaink, Herman P.; van den Thillart, Guido.

First draft genome sequence of the Japanese eel, Anguilla japonica. Gene 2012 ;Volum 511. s. 195-201

 

Hildahl, Jon Paul; Sandvik, Guro Katrine; Lifjeld, Rikke; Hodne, Kjetil; Nagahama, Y; Haug, Trude M; Okubo, Kataaki; Weltzien, Finn-Arne.

Developmental Tracing of Luteinizing Hormone b-Subunit Gene Expression Using Green Fluorescent Protein Transgenic Medaka (Oryzias latipes) Reveals a Putative Novel Developmental Function. Developmental Dynamics 2012 ;Volum 241.(11) s. 1665-1677

 

Hodne, Kjetil; von Krogh, Kristine; Weltzien, Finn-Arne; Sand, Olav; Haug, Trude M.

Optimized conditions for primary culture of pituitary cells from the Atlantic cod (Gadus morhua). The importance of osmolality, pCO(2), and pH. General and Comparative Endocrinology 2012 ;Volum 178.(2) s. 206-215

 

Mazzeo, I.; Penaranda, David Sanchez; Gallego, Victor; Hildahl, Jon Paul; Nourizadeh-Lillabadi, Rasoul; Asturiano, Juan F; Perez, L; Weltzien, Finn-Arne.

Variations in the gene expression of zona pellucida proteins, zpb and zpc, in female European eel (Anguilla anguilla) during induced sexual maturation. General and Comparative Endocrinology 2012 ;Volum 178.(2) s. 338-346

 

2011

Hildahl, Jon; Sandvik, Guro Katrine; Edvardsen, Rolf; Fagernes, Cathrine Elisabeth; Norberg, Birgitta; Haug, Trude M; Weltzien, Finn-Arne.

Identification and gene expression analysis of three GnRH genes in female Atlantic cod during puberty provides insight into GnRH variant gene loss in fish. General and Comparative Endocrinology 2011 ;Volum 172.(3) s. 458-467

 

Hildahl, Jon; Sandvik, Guro Katrine; Edvardsen, Rolf; Norberg, Birgitta; Haug, Trude M; Weltzien, Finn-Arne.

Four gonadotropin releasing hormone receptor genes in Atlantic cod are differentially expressed in the brain and pituitary during puberty. General and Comparative Endocrinology 2011 ;Volum 173.(2) s. 333-345

 

Published 18. November 2018 - 12:00 - Updated 2. March 2020 - 14:49