Cover image for the SmartSense4Protein project webpage
Photo: Pranish Karki

Smart Sensing platform for protein and peptide analysis

2025 - 2029

Research Council of Norway
NFR-353091

About the SmartSense4Protein project

  • Project summary

    The project focuses on developing a smart sensor platform designed for analysis of proteins and peptides, aiming to contribute to the utilisation and upcycling of sustainable protein resources. Tackling the urgent requirement for novel protein sources in food and feed production, particularly within Norway's green and blue sectors, as well as the growing demand for protein-based nutraceuticals and biopharmaceuticals, present a substantial challenge. Due to high variations in raw materials and production processes, new sensors are urgently needed to monitor, develop and control processes. The SmartSense4Proteins project builds upon a new tunable laser emitting in the protein range of the mid-infrared spectrum developed in the HORIZON 2020 RIA PHOTONFOOD under coordination of NMBU and on artificial intelligence for bioprocess control developed in the SFI DigiFoods under coordination of NOFIMA. Due to its miniaturized size and low production costs, the laser is perfectly suited for the development of small and economical sensors in industrial settings. A versatile custom-made sample interaction module for monitoring proteins and peptides will be developed. A new hybrid digital twin concept that combines first-principle modelling with data modelling for process monitoring, control, and optimisation will be established. As an important case study, the project will focus on protein hydrolysis which is an important process for breaking down proteins into amino acids and small peptides with improved bioavailability and functionality. The project team brings together expertise in photonics, AI, robotics and metrology, with the latter playing a pivotal role in bridging the gap between photonics, robotics and AI research and the practical implementation of this technology in the industry. The project aims at close collaboration with industries within the protein hydrolysis sector to ensure user relevance and acceptance facilitated by experts in social life cycle analysis.

  • Participants at NMBU