Hopp til hovedinnhold
  1. Hjem
  • Kontakt oss
  • Bibliotek
  • NMBU-student
  • English site
  • Logg inn
  • Studier
  • Forskning
  • Om NMBU
Meny
Finn ansatte     Nynorsk versjon English version
Sigbjørn Lien
  • Professor
    • Fakultet for biovitenskap
    • Institutt for husdyr- og akvakulturvitenskap
+4767232702
+4791353715
sigbjorn.lien@nmbu.no
Picture of Sigbjørn Lien
Rediger min side

I work as professor in genetics at NMBU where my main research interests are functional and comparative genomics, genome evolution and genetic variation related to the genetic architecture of complex traits. Over the last 15 years I have devoted much of my time to the development of Centre for Integrative Genetics (CIGENE, www.cigene.no), which has grown from a small molecular biology lab to Norway's foremost SNP genotyping facility and an internationally important genomics research lab devoted to understanding mechanisms and genetic architecture underlying important phenotypes. Together with our extensive national and international collaborative network, we have pioneered the development of high-throughput genotyping tools for several agriculture and aquaculture species and taken important roles in high-profile genome sequencing projects.

Our work on salmonid genomic research has flourished and I am currently leading, or co-leading, five large projects on salmon genomics and genome biology (together totalling to more than 120 MNOK). Key among these is the NRC/NMBU-ToppForsk project “TRANSPOSE: Transposable elements as agents of genome evolution and adaptation following a recent whole genome duplication”, where we exploit the advantages of state of the art long-read sequencing technology to upgrade the salmonid genome resources with >20 new chromosome-level assemblies, generated across the eleven main phylogenetic lineages of salmonids. These highly improved genome resources have enabled us to position and taxonomically categorize TE-families in the whole group of salmonid fishes and develop pangenomes incorporating SNPs and SVs in genome-graphs to portray biodiversity and explore adaptive divergence across phylogenetic groups and populations. 

Moreover, to advance our understanding of how variation in the blueprint of the salmonid genomes may lead to phenotypic variation I initiated the international collaboration on “Functional Annotation of All Salmonid Genomes – FAASG” (http://www.faasg.org/). My engagement in annotation of fish genomes has expanded as coordinator of the EU/RIA-H2020 project “AQUA-FAANG: Advancing European Aquaculture by Genome Functional Annotation”, developing  comprehensive maps of functional elements and epigenetic marks for the six commercially most important fish species within European aquaculture (among these Atlantic salmon and rainbow trout).

  • Fagfelt
    • Genomics
    • Genome biology
    • Genome evolution
    • Aquaculture
    • Animal Science
  • Publikasjoner
    Liste med publikasjoner fra min forskning. (Cristin)
  • Forskning & prosjekt

    Prosjekter

    TRANSPOSE
    TRANSPOSE will use salmonid fishes, which have a high load of TEs in their genome, as a model system to understand the functional roles of TEs in vertebrate evolution.

    REWIRED ─ The role of whole genome duplication in vertebrate adaptation
    In the REWIRED project, we will use salmonid fish, which underwent a genome duplication 100 million years ago, as a model system to study the importance of genome duplication in evolution of new gene functions and adaptation.

    GenoSysFat - Integrating genomics and systems biology to improve the capacity for synthesis, transport, and filet deposition of EPA/DHA in salmon
    How can we increase the omega-3 content of salmon that are fed sustainable feeds? A brand new map of the salmon's genome makes it much easier to characterize heritable differences in how well different salmon families utilize the various nutrients.

    DigiSal. Towards the Digital Salmon: From a reactive to a pre-emptive research strategy in aquaculture
    Systems biology will aid sustainability in salmon farming. Scarcity of fish oil has forced development of novel feedstuffs, challenging the salmon's metabolism as well as our understanding of it.

    Forskningsprosjekter med nettside utenfor NMBU

    LiceRESIST
    TRANSPOSE
    The Aqua Genome project
    REWIRED
    DigiSal
    GenoSysFat

    Forskningsområder

    Tema: 

    • Husdyr
    • Akvakultur
    • Biovitenskap

    Forskningsområder: 

    • Bioteknologi
    • Fellesfag landbruk og fisk
    • Fellesfag matematikk og naturvitenskap

NMBU

  • Om NMBU
  • Studier
  • Forskning
  • Samarbeid
  • Sidekart
  • Personvern

Snarveier

  • Finn en ansatt
  • Beredskap / Vakt
  • Visuell profil
  • Bibliotek
  • Nyhetsbrev
  • Ledige stillinger

For studenter

  • Emnesøk
  • Canvas
  • Studenttinget
  • Studentweb
  • Studentliv
  • SiÅs

For forskere

  • Finansiering
  • Utdanning
  • EUs rammeprogram
  • Rådgivning og juss
  • Forske i utlandet

For ansatte

  • Verktøy og tjenester
  • Læringssenteret
  • Interne nettsider
  • Kompetanse
  • Webmail

For media

  • Aktuelt
  • Pressemeldinger PhD
  • Ekspertlister
  • Presserom
  • Offentlig journal
  • Byggeprosjekter

NMBU - Norges miljø- og biovitenskapelige universitet

Kontakt oss

Telefon 67 23 00 00

Faks 67 23 06 91

E-post post@nmbu.no

Mer kontaktinfo

Besøk oss

Campus Ås

Universitetstunet 3

1433 Ås

Kart: Mazemap / (pdf)

 

Følg oss
Facebook
Twitter
Instagram