Course code KJM410

KJM410 Organic Mass Spectrometry (MS)

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Showing course contents for the educational year 2016 - 2017 .

Course responsible: Dag Ekeberg
Teachers: Hanne Marie Devle, Roland Peter Kallenborn
ECTS credits: 10
Faculty: Faculty of Chemistry, Biotechnology and Food Science
Teaching language: EN, NO
(NO=norsk, EN=Engelsk)
Limits of class size:
40 (KJM313 + KJM410).
Teaching exam periods:
This course starts in Autumn parallel. This course has teaching/evaluation in Autumn parallel.
Course frequency: Annually
First time: Study year 2003-2004
Course contents:
The course covers the following types of mass spectrometry: sector instruments, quadrupole instruments, time of flight instruments, and ion cyclotron resonance instruments. The course also covers the interpretation of mass spectra and the types of interface used for different types of analyses.
Learning outcome:

The students will obtain both practical and theoretical background for using mass spectrometry, e.g. GC-MS, MALDI-MS and LC-MS. They will be able to use mass spectrometry for identifying organic and biological compounds.

Candidates will get familiar with the various techniques used to separate ions in a mass spectrometer, such as quadrupole (Q), sector instruments (B and ESA), TOF, ion traps and FT-ICR.

Interpretation of mass spectra is a central topic in the course and the students will spend time interpreting structures. Students will become familiar with the theory behind the different fragmentations of various compounds formed by different ionization techniques.

Learning activities:
Teaching support:

Office hours will be announced at the beginning of the semester.


"Mass Spectrometry, principles and applications", by Edmond de Hoffmann and Vincent Stroobant. ISBN 978-0-470-03311-1
General chemistry, KJM100 or equivalent. Organic chemistry, KJM210 or equivalent. Analytic chemistry, KJM240 or equivalent.
Recommended prerequisites:
KJM310 Chromatography or equivalent. KJM311 Organic Spectroscopy or equivalent. KJB200 Biochemistry or equivalent.
Mandatory activity:
Semester assignment.
Final oral examination.
Nominal workload:
Lectures given is 26 hours Preparation for lectures are 40 hours Individual study 234 hours
Entrance requirements:
Special requirements in Science
Reduction of credits:
For students who have completed KJM313: 8 credits' reduction.
Type of course:
2 hours of lecturing a week.
External examiner.
Examination details: Oral exam: Bestått / Ikke bestått