Course code BIO321

BIO321 Population Genetics and Molecular Evolution

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Showing course contents for the educational year starting in 2021 .

Course responsible: Peer Berg
Teachers: Simen Rød Sandve
ECTS credits: 10
Faculty: Faculty of Biosciences
Teaching language: EN
(NO=norsk, EN=Engelsk)
Teaching exam periods:
This course starts in Autumn parallel. This course has teaching/evaluation in Autumn parallel, .
Course frequency: Annually
First time: 2003H
Course contents:
Topics: Genetic Variation, The Hardy-Weinberg Principle, Recombination, Linkage and Disequilibrium, Basic Models for Natural Selection, Mutation, Genetic Drift, Inbreeding, Non-random mating, Population subdivision and Gene Flow, Molecular Population Genetics, Molecular Evolution, and Phylogenetics. Advanced Models for Natural Selection and Quantitative Genetics.
Learning outcome:

Course contents:

Topics: Genetic Variation, The Hardy-Weinberg Principle, Recombination, Linkage and Disequilibrium, Basic Models for Natural Selection, Mutation, Genetic Drift, Inbreeding, Non-random mating, Population subdivision and Gene Flow, Molecular Population Genetics, Molecular Evolution, and Phylogenetics. Advanced Models for Natural Selection and Quantitative Genetics.

Learning outcome:

Knowledge: Students will

  • acquire a thorough understanding of population genetics
  • be able to describe effects of population genetic forces on evolution and how it can be detected in molecular data
  • understand the dynamics of the evolutionary changes that happen at the molecular level
  • be able to explain the evolutionary forces and the evolutionary effects of different molecular mechanisms on genomes, genes and gene products
  • gain theoretical insight in methods used in comparative and phylogenetic analyses based on molecular data

SKILLS: Students will be able to

  • test for the effects of evolutionary forces affecting allele and gene frequencies
  • use a critical approach towards the interpretation of population genetic and evolutionary molecular data
  • understand cutting edge research articles on the subject

GENERAL COMPETENCES

Students will acquire

  • practical skills in methods used in comparative and phylogenetic analyses based on molecular data
  • understanding of the dynamics resulting in evolutionary changes in allele and genotype frequencies
Learning activities:
Lectures. Exercises and discussions of papers. Two compulsory assignments/computer exercises have to be handed in. Calculations/colloquia orgainzed by students.
Teaching support:
Canvas will be used actively to distribute information and links to computer programs, websites and data.
Syllabus:
Textbook: Philip W. Hedrick: Genetics of populations, 2011, Jones and Bartlett Publishers, LLC.
Prerequisites:
BIO120 - Introduction to Genetics, MATH100 - Introductory Mathematics, STAT100 - Statistics.
Recommended prerequisites:
BIO211 - Molecular Biology, BIO220 - Eukaryotic Molecular Biology /BIO200 Molecular Genetics in Eukaryots, BIO223  Molecular Ecology and Evolution
Mandatory activity:
Compulsory assignments must be approved before the student can attend the final oral examination.
Assessment:
Oral examination counts 100%.
Nominal workload:

250 hours

Lectures: 24 hours. Exercises and discussions of papers: 24 hours. Individual study/colloquiums: 202 hours.

Entrance requirements:
Special requirements in Science
Type of course:
Lectures: 2 hours per week for 12 weeks. Exercises: 2 hours per week for 12 weeks.
Examiner:
An external examiner will take part in the oral examination
Examination details: Oral exam: A - E / F