Course code KJM314

KJM314 Applied Organic Analytical Chemistry

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Showing course contents for the educational year 2014 - 2015 .

Course responsible: Roland Peter Kallenborn
Teachers: Laura Röhler, Dag Ekeberg, Morten Sørlie, Yngve Henning Stenstrøm
ECTS credits: 10
Faculty: Department of Chemistry, Biotechnology and Food Science
Teaching language: EN, NO
(NO=norsk, EN=Engelsk)
Limits of class size:
Minimum 6.
Maximum 20.
Teaching exam periods:
This course starts in the autumn semester This course has teaching/evaluation in the autumn semester .
Course frequency: Annually
First time: 2012V
Preferential right:
Course contents:

The course will focus on various applications for organic analytical chemistry:

  • HPLC: for purification and isolation of organic compounds
  • GC/MS and GC/ECD: within environmental chemistry and pollution
  • LC/MS, GC/MS and GC/FID: for product control in technical applications and synthesis
  • LC/MS and GC/MS: for purification and product control within drug production.

Critical method validation and quality control will be integrated in both lectures and practice.

Learning outcome:
A practical guidance is provided into the analytical organic chemistry as a versatile tool in a variety of applications spanning from technical control, product control to pharmaceutical application, environmental chemistry and medical/ health related applications.
The course will be designed as a combination of lectures and practical exercises where basic methods in organic analytical chemistry will be applied for specific technical tasks and problem oriented solutions (method validation, concentration determination, product control etc.). Quantitative standard methods like GC/MS, LC/MS, GC/ECD, GC/FID as well as purification methods like GPC/SEC, Ion-exchange chromatography, Silica based, Alumina-based chromatography will be applied and evaluated.
After completion, the candidates should have knowledge of, and be familiar with, the various analytical techniques used for sample purification and quantitative analysis using a variety of separation and detection techniques, including mass spectrometry, UV-VIS detection etc. Interpretation of chromatograms and quantification procedures are central topics. Students will become familiar with the validation of methods for specific applications and will be able to select appropriate methods for a specific application within the field of organic analytical chemistry.
Learning activities:
There will be lectures and seminars where students are expected to be involved in a constructive and active way. Students are given a project to work on and present in plenary. A lab journal must be handed in; it will be evaluated before the written exam. 
Teaching support:
Office hours will be announced. Seminars will be held in which the laboratory work is discussed. 
Lecture printouts as well as selected scientific publications.
The course is based on scientific knowledge in generell Chromatography and Mass Spectrometry (may be taken in parallel).
Recommended prerequisites:
A good understanding of the general principles and methods in organic analytical chemistry is a prerequisite for the successful completion of the course KJM 314.
Mandatory activity:
Experimental assignments and presentations to be presented in plenum.

3 hours written exam, counts 60 %

Written report, counts 40 %

Nominal workload:
Lectures: 52 hours.
Practical exercises: 78 hours.
Individual study: 170 hours (including project work).
Entrance requirements:
Special requirements in Science
Reduction of credits:
Type of course:
4 hours with lectures/ seminars and 6 hours with laboratory exercises per week.
An external examiner approves the examination questions and marks 25 randomly selected examination papers.
Allowed examination aids: All types of calculators, all other aids.
Examination details: Continuous exam: A - E / Ikke bestått