Course code KJM313

KJM313 Mass Spectrometry

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Showing course contents for the educational year 2022 - 2023 .

Course responsible: Dag Ekeberg
ECTS credits: 10
Faculty: Faculty of Chemistry, Biotechnology and Food Science
Teaching language: EN, NO
(NO=norsk, EN=Engelsk)
Teaching exam periods:
This course starts in the Autumn parallel. This course has teaching/evaluation in Autumn parallel.
Course frequency: Annually
First time: Study year 2007-2008
Preferential right:
Students in the Master's Programme in Chemistry (M-KJEMI) and in the Master's programme in Technology, specialization Chemistry and Biotechnology (M-KB).
Course contents:

The course deals with the following types of mass spectrometers: sector, quadrupole, time of flight and ion trap instruments. The course deals with the interpretation of mass spectra, and the type of ionization methods used for different analyzes.

In the rhetorical presentation of the course, emphasis is placed on pathos together with ethos and logos to provide a verbal presentation that creates understanding among students and others who participate in the teaching.

The UN's sustainability goals are the world's joint work plan to eradicate poverty, fight inequality and stop climate change by 2030. Sustainable development is about meeting the needs of us humans living today, without destroying future generations' ability to meet their needs. The sustainability goals reflect the three dimensions of sustainable development: climate and environment, economy and social conditions. This course is not a course in these sustainability goals, but it is structured so that we can meet some of these goals, such as goals no. 4, 5, 6, 9, 12, 13.

Learning outcome:


  • The student will have advanced knowledge in theoretical use of mass spectrometry
  • The student will have advanced knowledge in practical use of mass spectrometry
  • The student will be able to use mass spectrometry for identifying organic and biological compounds. 


Candidates should acquire skills in various techniques for filtering ions in different mass filters. The most important mass filters under review are quadrupole, triple quadrupole, cylindrical and ion traps, Orbitrap, time-of-flight and sector instruments. Spectrum interpretation is very late in the subject.

Generell competence

After completing the course, the students should have general competence in the theory behind the different fragmentations of different compounds by different ionization methods. You should be able to interpret EI mass spectra. Students should be able to communicate about how to prepare and present technical and scientific information, both with specialists and to the general public.

Learning activities:
Teaching support:
Office hours will be announced at the beginning of the semester. Questions sent via email  or Canvas will also be answered. A dedicated FaceBook page has been created for those who take the course where everyone can participate in professional discussions.
"Mass Spectrometry, principles and applications", by Edmond de Hoffmann and Vincent Stroobant. ISBN 978-0-470-03311-1
It is assumed that the student knows the rules within plagiarism and cheating, as well as how to refer when writing a text.Organic chemistry, KJM210 (or equivalent)Analytic chemistry, KJM240 (or equivalent)Physical chemistry, KJM230 (or equivalent)

Recommended prerequisites:
KJM310, Chromatography or equivalent.

Reflection video uploaded to Wiseflow, digital final exam with external examiner (7 hours): 100% of the total grade, A-F.

Aids: C3: all types of calculators, all other aids - including digital.

Nominal workload:
  • Lectures: 26 hours 
  • Lecture preparation: 40 hours
  • Self-study: 184 hours
Entrance requirements:
Special requirements in Science
Type of course:
2 hours of lecturing a week.
An external examiner approves the examination questions and marks all exams.
Examination details: Home exam: Letter grades