Course code BIO421

BIO421 Population Genetics and Molecular Evolution

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Showing course contents for the educational year starting in 2019 .

Course responsible: Siri Fjellheim
Teachers: Jørn Henrik Sønstebø
ECTS credits: 15
Faculty: Faculty of Biosciences
Teaching language: EN
(NO=norsk, EN=Engelsk)
Teaching exam periods:
This course starts in Autumn parallel. This course has teaching/evaluation in Autumn parallel, .
Course frequency: Annually
First time: 2011H
Preferential right:
PhD students
Course contents:
Topics: Genetic Variation, The Hardy-Weinberg Principle, Recombination, Linkage and Disequilibrium, Basic Models for Natural Selection, Mutation, Genetic Drift, Inbreeding, Nonrandom Mating, Population Subdivision and Gene Flow, Molecular Population Genetics, Molecular Evolution, Phylogenetics, Advanced Models for Natural Selection, Quantitative Genetics.
Learning outcome:
The students should be able to understand the dynamics of the evolutionary changes that happen at the molecular level, the evolutionary forces behind such changes and the evolutionary effects of different molecular mechanisms on genomes, genes and gene products. The students should also gain theoretical insight and practical skills in methods used in comparative and phylogenetic analyses based on molecular data. The students should develop a critical approach towards the interpretation of this type of data, and a level of knowledge sufficient to understand cutting edge research articles on the subject. The students should be able to plan their own research on the subject and apply relevant methods in order to analyse and present the results.
Learning activities:
Lectures. Exercises and discussion of papers. Two compulsory assignments/computer exercises have to be handed in. Calculations/colloquia organized by students.Individual supervision as regards relevant articles for preparing the semester assignment.
Teaching support:
Canvas will be used actively to distribute information and links to computer programs, websites and data.
Syllabus:
Textbook: Philip W. Hedrick: Genetics of populations, 2011, Jones and Bartlett Publishers, LLC.
Prerequisites:
BIO120 - Introduction to Genetics,MATH100 - Introductory Mathematics, STAT100 - Statistics.
Recommended prerequisites:
BIO211 - Molecular Biology, BIO220 Eukaryotic Molecular Biology /BIO200 Molecular Genetic in Eukaryots, BIO223 Molecular Ecology and Evolution
Mandatory activity:
Two compulsory assignments/computer exercises have to be handed in.
Assessment:
Oral examination based on the complete syllabus counts 2/3, and evaluation and oral examination of the term paper counts 1/3 towards the final grade. Both parts must be passed.
Nominal workload:
Lectures: 24 hours. Exercises and discussions: 24 hours. Course readings, writing and presentation of a semester assignment and individual study: 402 hours.
Entrance requirements:
Special requirements in Science
Reduction of credits:
Credit reduction in relation to BIO321: 10 credits.
Type of course:
Lectures: 2 hours per week for 12 weeks. Exercises: 2 hours per week for 12 weeks.Presentation and discussion of semester assignment: 3 hours.
Examiner:
An external examiner will take part in the oral examination and read the term paper
Examination details: Continous exam and oral exam: Bestått / Ikke bestått