Course code BIO322

BIO322 Molecular Genomics

There may be changes to the course due to to corona restrictions. See Canvas and StudentWeb for info.

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Showing course contents for the educational year 2021 - 2022 .

Course responsible: Dag Inge Våge, Marie Saitou
ECTS credits: 10
Faculty: Faculty of Biosciences
Teaching language: EN, NO
(NO=norsk, EN=Engelsk)
Limits of class size:
If there are fewer than 5 participants, the course will be offered as individual study with supervised project work.
Teaching exam periods:
This course starts in Autumn parallel. This course has teaching/evaluation in Autumn parallel.
Course frequency: Annually
First time: 2003H
Preferential right:
Bioinformatics, Biotechnology, Genome Science, Animal Science, Plant Science.
Course contents:
The course content is the structure and regulation of complex genomes, and the technologies used to study genomes. Subjects to be covered include comparative genomics, evolutionary genomics, genetic and physical mapping of genomes, gene expression, genome regulation analysis, proteome analysis, and functional genome annotation. Learning activities include lectures, reading and presentations, and computer hands-on practice.
Learning outcome:

A candidate who has completed the course is expected to have achieved the following learning outcomes, defined in terms of knowledge, skills and general competence:

Knowledge Can explain the elements that define the structure of eukaryotic genomes and explain the role of genetic regulation at the cellular and molecular levels.

Can explain how genomic variation is generated and maintained in populations, and how variation contributes to evolution.

Can explain the basic molecular processes occurring when using key technologies for DNA and RNA sequencing, genotyping, and protein analysis.

Can explain how data generated by the above mention technologies can be applied in comparative analyses, evolutionary genomics, genetic and physical mapping of genomes, gene and protein expression, genome regulation analysis, and functional genome annotation.

Can explain how genome technologies are applied in conservation and in industry, such as ecology (e.g. biodiversity measurement), agri/aquaculture (e.g. genome-informed breeding), and medicine (e.g. generating RNA vaccines).

Can identify and reflect on ethical issues related to exploiting genomic technologies and genomic data.

Skills Students can read and explain/present scientific papers in genomics.

Students can use online tools and databases to retrieve and analyze genomic data.

Students can describe the molecular biological, statistical and computational basis of genetic analyses and interpret analyses of genomic data.

Students can work independently and in groups to solve practical and theoretical problems, including oral presentation, data analysis, and written reports.

General competence Can communicate and discuss scientific questions, analyses, and conclusions in this field, both with peers and laymen.

Students can combine information from different sources to gain new insight.

Learning activities:
Learning activities include lectures, reading and presentations, and computer hands-on practice.
Teaching support:
Can be found at the BIO322-Canvas pages.
BIO210/211 and/or BIO200.
Recommended prerequisites:
Mandatory activity:
Yes.The practical assignments that must be approved before the exam can be completed.
The final exam is a multiple choice test. The practical assignments must be approved before the exam can be completed.
Nominal workload:
250 hours.
Entrance requirements:
Special requirements in Science
Reduction of credits:
Type of course:
Lectures/practicals, student presentations of review papers.
Details concerning the teaching arrangements and assessment are discussed with the external censor. The written exam is evaluated by the censor.
Allowed examination aids: A1 No calculator, no other aids
Examination details: Written exam: A - E / F