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Quantitative Genetics Applied in Animal Breeding

  • Photo: 
    Janne Karin Brodin, NMBU

NOVA PhD course of 3 ECTS, organised by Prof. Pekka Uimari, University of Helsinki - Faculty of Agriculture and Forestry.
Preliminary course dates and location: Aug. 2018, in Mikkeli, Finland.

Course Description
The course will focus on population and quantitative genetics that is relevant in animal breeding. The course is aimed at students with an interest in quantitative genetics or animal breeding. 

The course will focus on understanding, analysing, and utilizing the genetic basis of quantitative traits for animal breeding and genetics, with a focus on application in the genomic selection era.

Programme Outline
The lectures will cover the following topics: Basics of quantitative traits and quantitative variation, Genotypic variance and its components, The normal distribution and the infinitesimal model, Variance components estimation and heritability, Epistasis, Relatedness among relatives, the relationship matrix, Inbreeding and heterosis, The multivariate normal distribution, two-trait models, genetic and environmental correlation, genotype by environment interactions, norm of reaction, Maternal effects, Genetic drift, Wright’s F statistics, FST, FIS, effective population size, factors affecting Ne, Linkage disequilibrium, haplotypes, the Bulmer effect, QTL mapping, genetic markers, association studies, Quantitative genetics of genomic models. Some of the topics will be covered with independent study prior and during the course. The lectures are accompanied with practicals.

Learning Outcomes
After the course the students should have comprehensive understanding of population and quantitative genetics applied in animal breeding. The main emphasis of the course is to cover topics that are especially relevant in the current genomic based breeding era.

Evaluation Elements
During the course: results of the problem sets will be presented, discussed and evaluated daily in the class. The results of the problem sets will be presented and discussed jointly in the class in feedback sessions.

Pedagogical Approach
The pedagogical approach will combine lecturing with problem based and collaborative learning methods. The goal is to improve students’ skills and tools to make use of the current theories and applications in their own research work, as well as, improve their capabilities to embrace new techniques and approaches that are likely to be developed in the near future. The course will also provide the participants important contacts with internationally recognized teachers and other Nordic students working in the same field.

Estimated Workload

  • 20 hours seminar
  • 30 hours lecture
  • 40 hours independent work

Prerequisite Knowledge
Basic knowledge of quantitative genetics and algebra. Very basic knowledge of matrix algebra and basic familiarity with linear models. An MSc-degree in animal breeding and genetics or a related field suffices.

Admission for NOVA courses is handled by the course organiser/ the NOVA member institution organising the course. Please see the links in the margin for more information.

Published 19. June 2017 - 12:55 - Updated 19. June 2017 - 13:04

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