The course will focus on population and quantitative genetics that is relevant in the genomic selection era. The course is aimed at students with an interest in quantitative genetics or animal breeding.
The course will focus on understanding, analysing, and utilizing the genetic basis of quantitative traits for animal breeding and genetics, with a focus on application in the genomic selection era.
- Lecture 1: Basic single locus genetics. Fisher’s decomposition of the genotypic value. Average effect & Breeding value.
- Lecture 2: Forces changing allele frequency: mutation, selection, drift. Effective population size.
- Lecture 3: Coalescence theory.
- Lecture 4: Multilocus genetics. Forces generating linkage disequilibrium: mutation, selection, drift.
- Lecture 5: Long-term response to selection. The effective number of segments in the genome.
- Lecture 6: Relationship matrices based on markers; scaling of relationships and definition of a base generation, Wright’s F-statistics.
- Lecture 7: The accuracy of genomic selection and its dependency on genome structure.
- Lecture 8: Variation in relatedness.
- Lecture 9: Prediction of response to genomic selection using selection index theory.
- Lecture 10: Breeding programs with genomic selection.
- Prof. Piter Bijma, Wageningen University
Please find more information on the course and how to apply on the course information website: