New article on gonadotrope cell plasticity

New article on gonadotrope cell plasticity

  • In situ hybridization image of the medaka pituitary gland.
    Photo
    Romain Fontaine

Our group just published a new article in Journal of Endocrinology where we investigated the plasticity of gonadotropes in the model fish medaka.

New article on gonadotrope cell plasticity

Using a combination of in vivo and in vitro experiments, our results reveal high plasticity of gonadotropes due to both estradiol-sensitive proliferation and Gnrh-promoted phenotypic conversion, and moreover show that gonadotropes lose part of their identity when kept in cell culture.

Fontaine, R., Ager-Wick, E., Hodne, K., & Weltzien, F. (2020). Plasticity in medaka gonadotropes via cell proliferation and phenotypic conversion, Journal of Endocrinology, 245(1), 21-37.

Published 2. March 2020 - 14:46 - Updated 2. March 2020 - 14:46